Heart failure and diabetes: Pathogenesis and management

Research output: Contribution to journalReview article


The incidence of diabetes among patients with congestive heart failure (CHF) is increasing. Despite advances in therapy for CHF, mortality remains about 30% higher for diabetics with CHF than non-diabetics. Multiple mechanisms are responsible for development of CHF in diabetes with ischemic heart disease and its attendant complication of left ventricular dysfunction playing a major role. The prevalence of diabetes is rising worldwide. Thus in the foreseeable future, it appears that physicians will have to deal with increasing numbers of subjects with diabetes, coronary disease and heart failure. Management of diabetes and comorbid conditions plays a vital role in the prevention of development CHF in subjects with diabetes. Treatment of asymptomatic left ventricular dysfunction and management of CHF has been evolving over last few years with major clinical trials advancing our knowledge. This review highlights some of the new developments in this field.

Original languageEnglish (US)
Pages (from-to)231-239
Number of pages9
JournalMinerva Medica
Issue number3
StatePublished - Jun 1 2006


  • Diabetes
  • Heart failure, congestive, physiopathology
  • Heart failure, congestive, therapy

ASJC Scopus subject areas

  • Medicine(all)

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