Heart failure and long-term survival among older women with breast cancer

Jordan M. Harrison, Christopher R. Friese, Debra L. Barton, Nancy K. Janz, Susan Pressler, Matthew A. Davis

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVES: To evaluate the association between heart failure and overall survival up to 10 years after breast cancer diagnosis. SAMPLE & SETTING: Women aged 65 years or older diagnosed with invasive breast cancer, with and without self-reported heart failure, were examined for this retrospective cohort study using Surveillance, Epidemiology, and End Results cancer registries in the United States. METHODS & VARIABLES: Cox proportional hazards regression was used to examine the association between heart failure status and mortality, adjusting for comorbidity and other clinical or sociodemographic differences. Associations were examined overall and stratified by cancer stage. RESULTS: In adjusted models, having heart failure was associated with increased likelihood of death up to 10 years after cancer diagnosis. In adjusted subanalyses by cancer stage, heart failure was associated with increased likelihood of death up to 10 years after cancer diagnosis in women with stage I or II cancer but not in women with stage III/IV cancer. IMPLICATIONS FOR NURSING: Although early-stage breast cancer is generally associated with better prognosis, the competing mortality risk of heart failure was greater for this group than for women with advanced cancer. Prevention and management of cardiovascular disease should be prioritized for this patient subgroup.

Original languageEnglish (US)
Pages (from-to)77-87
Number of pages11
JournalOncology Nursing Forum
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

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Heart Failure
Breast Neoplasms
Survival
Neoplasms
Mortality
Registries
Comorbidity
Epidemiology
Cohort Studies
Cardiovascular Diseases
Retrospective Studies

Keywords

  • Breast cancer
  • Comorbidities
  • Heart failure
  • Late effects
  • Survivorship

ASJC Scopus subject areas

  • Oncology(nursing)

Cite this

Harrison, J. M., Friese, C. R., Barton, D. L., Janz, N. K., Pressler, S., & Davis, M. A. (2018). Heart failure and long-term survival among older women with breast cancer. Oncology Nursing Forum, 45(1), 77-87. https://doi.org/10.1188/18.ONF.77-87

Heart failure and long-term survival among older women with breast cancer. / Harrison, Jordan M.; Friese, Christopher R.; Barton, Debra L.; Janz, Nancy K.; Pressler, Susan; Davis, Matthew A.

In: Oncology Nursing Forum, Vol. 45, No. 1, 01.01.2018, p. 77-87.

Research output: Contribution to journalArticle

Harrison, JM, Friese, CR, Barton, DL, Janz, NK, Pressler, S & Davis, MA 2018, 'Heart failure and long-term survival among older women with breast cancer', Oncology Nursing Forum, vol. 45, no. 1, pp. 77-87. https://doi.org/10.1188/18.ONF.77-87
Harrison, Jordan M. ; Friese, Christopher R. ; Barton, Debra L. ; Janz, Nancy K. ; Pressler, Susan ; Davis, Matthew A. / Heart failure and long-term survival among older women with breast cancer. In: Oncology Nursing Forum. 2018 ; Vol. 45, No. 1. pp. 77-87.
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