Hemodynamic assessment of local anesthetic administration by laser Doppler flowmetry

Elie M. Fernieini, Jeffrey D. Bennett, David G. Silverman, Thomas M. Halaszynski

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective. The hemodynamic effects of local anesthetic administration with and without a vasoconstrictor were compared by using laser Doppler flowmetry. Study design. Seventeen people participated in a single study session in which they were given 2 intraoral injections. The injections, which were administered in random order, consisted of 1.8 mL lidocaine (2%) with epinephrine (1:100,000) and mepivacaine (3%). Hemodynamic parameters consisting of blood pressure, heart rate, and laser Doppler flowmetry were reordered at regular intervals. Results. The laser Doppler flowmeter detected changes in the peripheral perfusion of the finger that were not detected by changes in blood pressure and heart rate. The greatest change was associated with anxiety and occurred just before the injection. The inclusion of epinephrine in the local anesthetic resulted in a persistence of these changes. Conclusion. This investigation has confirmed the sensitivity of laser Doppler flowmetry as an investigational tool for assessing hemodynamic changes associated with anxiety and the administration of local anesthesia.

Original languageEnglish (US)
Pages (from-to)526-530
Number of pages5
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Volume91
Issue number5
DOIs
StatePublished - May 2001
Externally publishedYes

Fingerprint

Laser-Doppler Flowmetry
Local Anesthetics
Hemodynamics
Epinephrine
Injections
Anxiety
Heart Rate
Mepivacaine
Blood Pressure
Flowmeters
Vasoconstrictor Agents
Local Anesthesia
Lidocaine
Fingers
Lasers
Perfusion

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Surgery
  • Dentistry(all)

Cite this

Hemodynamic assessment of local anesthetic administration by laser Doppler flowmetry. / Fernieini, Elie M.; Bennett, Jeffrey D.; Silverman, David G.; Halaszynski, Thomas M.

In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, Vol. 91, No. 5, 05.2001, p. 526-530.

Research output: Contribution to journalArticle

Fernieini, Elie M. ; Bennett, Jeffrey D. ; Silverman, David G. ; Halaszynski, Thomas M. / Hemodynamic assessment of local anesthetic administration by laser Doppler flowmetry. In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 2001 ; Vol. 91, No. 5. pp. 526-530.
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