Hepatocellular carcinoma occurring in a patient with Crohn's disease treated with both azathioprine and infliximab

Shawn C. Chen, Oscar Cummings, Michael P. Hartley, Carol A. Filomena, Won Kyoo Cho

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Hepatocellular carcinoma is known to be associated with underlying liver diseases, such as cirrhosis, hemochromatosis, and chronic viral hepatitis. All reported cases of hepatocellular carcinoma in association with Crohn's disease involve patients treated previously with azathioprine or both azathioprine and steroids. However, hepatocellular carcinoma associated with the use of azathioprine and infliximab has not been reported. In this report, we describe an unusual case of hepatocellular carcinoma and focal hepatic glycogenosis (FHG) occurring in a non-cirrhotic Crohn's disease patient who has been treated with both azathioprine and infliximab.

Original languageEnglish
Pages (from-to)952-955
Number of pages4
JournalDigestive Diseases and Sciences
Volume51
Issue number5
DOIs
StatePublished - May 2006

Fingerprint

Azathioprine
Crohn Disease
Hepatocellular Carcinoma
Glycogen Storage Disease
Hemochromatosis
Chronic Hepatitis
Liver Diseases
Fibrosis
Steroids
Infliximab
Liver

Keywords

  • Azathioprine
  • Crohn's disease
  • Focal hepatic glycogenosis
  • Hepatocellular carcinoma
  • Infliximab

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hepatocellular carcinoma occurring in a patient with Crohn's disease treated with both azathioprine and infliximab. / Chen, Shawn C.; Cummings, Oscar; Hartley, Michael P.; Filomena, Carol A.; Cho, Won Kyoo.

In: Digestive Diseases and Sciences, Vol. 51, No. 5, 05.2006, p. 952-955.

Research output: Contribution to journalArticle

Chen, Shawn C. ; Cummings, Oscar ; Hartley, Michael P. ; Filomena, Carol A. ; Cho, Won Kyoo. / Hepatocellular carcinoma occurring in a patient with Crohn's disease treated with both azathioprine and infliximab. In: Digestive Diseases and Sciences. 2006 ; Vol. 51, No. 5. pp. 952-955.
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