Hereditary amyloidosis: description of a new american kindred with late onset cardiomyopathy

Merrill D. Benson, Margaret R. Wallace, Eduardo Tejada, Hal Baumann, Burnestine Page

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

A family with hereditary amyloidosis characterized by peripheral neuropathy and cardiomyopathy is described. Lack of eye involvement sets their disease apart from the Indiana/Swiss familial amyloidotic polyneuropathy type II. The disease is of late onset; affected members die of cardiomyopathy after age 60. The late onset and lack of clinically significant neuropathy in several family members had led to misdiagnosis of the cardiomyopathy. Immunohistochemistry using antiprealbumin antiserum showed staining of amyloid deposits in nerve and heart.

Original languageEnglish (US)
Pages (from-to)195-200
Number of pages6
JournalArthritis & Rheumatism
Volume30
Issue number2
DOIs
StatePublished - Feb 1987

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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