Heritability of EEG coherence in a large sib-pair population

David B. Chorlian, Yongqiang Tang, Madhavi Rangaswamy, Sean O'Connor, John Rohrbaugh, Robert Taylor, Bernice Porjesz

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

The additive genetic heritability of bipolar EEG coherence in a sample of 305 non-twin sibships comprising 690 individuals (age range 7-65) was estimated. Heritabilities were examined in 6 frequency bands for each of 15 coherence pairs, both interhemispheric and intrahemispheric. The heritabilities of the bipolar EEG coherence ranged from 0.22 to 0.63 in 79 of the 90 phenotypes which had coherences high enough to provide meaningful values for the estimation of heritability. Heritabilities were greatest in the low and high alpha frequency bands, while theta and beta bands had comparable heritabilities. Coherences themselves were greatest in the low and high alpha frequency bands, while theta coherences were somewhat larger than beta. Higher heritability values were not associated with higher coherences. The examination of bivariate genetic correlations suggests that there is a difference between theta and alpha bands in genetic control of interhemispheric coherence.

Original languageEnglish (US)
Pages (from-to)260-266
Number of pages7
JournalBiological Psychology
Volume75
Issue number3
DOIs
StatePublished - Jul 1 2007

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Keywords

  • Bipolar
  • Coherence
  • EEG
  • Heritability

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology

Cite this

Chorlian, D. B., Tang, Y., Rangaswamy, M., O'Connor, S., Rohrbaugh, J., Taylor, R., & Porjesz, B. (2007). Heritability of EEG coherence in a large sib-pair population. Biological Psychology, 75(3), 260-266. https://doi.org/10.1016/j.biopsycho.2007.03.006