Heterogeneity in Paget disease of the bone

Martha A. Nance, Frank Q. Nuttall, Michael Econs, Kenneth W. Lyles, Kristi D. Viles, Jeffery M. Vance, Margaret A. Pericak-Vance, Marcy C. Speer

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Paget disease of the bone is a common skeletal disorder. Recently, a gene for Paget disease was localized to 18q with subsequent evidence for linkage heterogeneity. We report the identification and clinical characterization of a large pedigree of Paget disease and demonstrate that the Paget disease gene in this pedigree is not linked to the region on 18q, thus confirming linkage heterogeneity. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)303-307
Number of pages5
JournalAmerican Journal of Medical Genetics
Volume92
Issue number5
DOIs
StatePublished - Jun 19 2000

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Osteitis Deformans
Pedigree
Genes

Keywords

  • Heterogeneity
  • Paget disease

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Nance, M. A., Nuttall, F. Q., Econs, M., Lyles, K. W., Viles, K. D., Vance, J. M., ... Speer, M. C. (2000). Heterogeneity in Paget disease of the bone. American Journal of Medical Genetics, 92(5), 303-307. https://doi.org/10.1002/1096-8628(20000619)92:5<303::AID-AJMG2>3.0.CO;2-E

Heterogeneity in Paget disease of the bone. / Nance, Martha A.; Nuttall, Frank Q.; Econs, Michael; Lyles, Kenneth W.; Viles, Kristi D.; Vance, Jeffery M.; Pericak-Vance, Margaret A.; Speer, Marcy C.

In: American Journal of Medical Genetics, Vol. 92, No. 5, 19.06.2000, p. 303-307.

Research output: Contribution to journalArticle

Nance, MA, Nuttall, FQ, Econs, M, Lyles, KW, Viles, KD, Vance, JM, Pericak-Vance, MA & Speer, MC 2000, 'Heterogeneity in Paget disease of the bone', American Journal of Medical Genetics, vol. 92, no. 5, pp. 303-307. https://doi.org/10.1002/1096-8628(20000619)92:5<303::AID-AJMG2>3.0.CO;2-E
Nance, Martha A. ; Nuttall, Frank Q. ; Econs, Michael ; Lyles, Kenneth W. ; Viles, Kristi D. ; Vance, Jeffery M. ; Pericak-Vance, Margaret A. ; Speer, Marcy C. / Heterogeneity in Paget disease of the bone. In: American Journal of Medical Genetics. 2000 ; Vol. 92, No. 5. pp. 303-307.
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