Highly Cross-Linked Versus Conventional Polyethylene in Posterior-Stabilized Total Knee Arthroplasty at a Mean 5-Year Follow-up

R. Michael Meneghini, Luke R. Lovro, Shelly A. Smits, Philip H. Ireland

Research output: Contribution to journalArticle

14 Scopus citations


Concerns of highly cross-linked polyethylene (XLPE) in total knee arthroplasty (TKA) exist regarding fatigue resistance and oxidation, particularly in posterior-stabilized (PS) designs. A prospective cohort study of 114 consecutive PS TKAs utilized conventional polyethylene in 50 knees and second-generation annealed XLPE in 64 TKAs. Clinical (Short-Form 36, Knee Society Scores, and LEAS) and radiographic outcomes were evaluated at a mean of 5 years in 103 TKAs. Mean KSS scores were 12 points higher (P= 0.01) and SF-36 physical function subset 14 points higher (P= 0.005) in the XLPE group. There was no radiographic osteolysis or mechanical failure related to the tibial polyethylene in either group. At 5-year follow-up, no deleterious effects related to highly cross-linked posterior stabilized tibial polyethylene inserts were observed.

Original languageEnglish (US)
Pages (from-to)1736-1739
Number of pages4
JournalJournal of Arthroplasty
Issue number10
StatePublished - Oct 1 2015



  • Annealed polyethylene
  • Fatigue failure
  • Highly-crosslinked
  • Polyethylene
  • Total knee arthroplasty
  • Total knee replacement

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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