HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures

B. I. Lee, Omkar Markand, H. N. Wellman, A. R. Siddiqui, B. Mock, J. Krepshaw, H. Kung

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

HIPDM-Single photon emission computed tomography brain imaging was performed during interictal and ictal stages in three patients with complex partial seizures and secondarily generalized tonic-clonic seizures. In all three patients, interictal studies demonstrated decreased regional cerebral perfusion (rCP) and ictal studies showed increased rCP in the epileptogenic region. The demonstration of focal hyperperfusion by SPECT performed during secondarily generalized tonic-clonic seizures suggests that rCP in the epileptic focus remains higher than in other cerebral regions during immediate postictal stages, even in secondarily generalized seizures.

Original languageEnglish
Pages (from-to)305-311
Number of pages7
JournalEpilepsia
Volume28
Issue number3
StatePublished - 1987
Externally publishedYes

Fingerprint

Single-Photon Emission-Computed Tomography
Neuroimaging
Seizures
Perfusion
Stroke
N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Lee, B. I., Markand, O., Wellman, H. N., Siddiqui, A. R., Mock, B., Krepshaw, J., & Kung, H. (1987). HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures. Epilepsia, 28(3), 305-311.

HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures. / Lee, B. I.; Markand, Omkar; Wellman, H. N.; Siddiqui, A. R.; Mock, B.; Krepshaw, J.; Kung, H.

In: Epilepsia, Vol. 28, No. 3, 1987, p. 305-311.

Research output: Contribution to journalArticle

Lee, BI, Markand, O, Wellman, HN, Siddiqui, AR, Mock, B, Krepshaw, J & Kung, H 1987, 'HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures', Epilepsia, vol. 28, no. 3, pp. 305-311.
Lee, B. I. ; Markand, Omkar ; Wellman, H. N. ; Siddiqui, A. R. ; Mock, B. ; Krepshaw, J. ; Kung, H. / HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic-clonic seizures. In: Epilepsia. 1987 ; Vol. 28, No. 3. pp. 305-311.
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