Histologic effects of radiation therapy and total androgen blockade on prostate cancer

David Grignon, W. A. Sakr

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Two commonly used therapies on prostate cancer - radiation and total androgen blockade - induce predictable histologic changes in the tumor tissue. With the increasing use of posttreatment biopsies to evaluate patients receiving radiation therapy and the use of neoadjuvant total androgen blockade before radical prostatectomy, recognition of these alterations is of considerable importance to pathologists. Additionally, the significance of the observed changes, as regards evaluating the therapeutic response, is of considerable interest. The purpose of this report is to review the current knowledge of these important issues.

Original languageEnglish (US)
Pages (from-to)1837-1841
Number of pages5
JournalCancer
Volume75
Issue number7 SUPPL.
StatePublished - 1995
Externally publishedYes

Fingerprint

Androgens
Prostatic Neoplasms
Radiotherapy
Prostatectomy
Radiation
Biopsy
Therapeutics
Neoplasms
Pathologists

Keywords

  • biopsy
  • hormone therapy
  • prostate gland
  • radiation
  • treatment effects

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Histologic effects of radiation therapy and total androgen blockade on prostate cancer. / Grignon, David; Sakr, W. A.

In: Cancer, Vol. 75, No. 7 SUPPL., 1995, p. 1837-1841.

Research output: Contribution to journalArticle

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