Histologic effects of radiation therapy and total androgen blockade on prostate cancer

David J. Grignon, Wael A. Sakr

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Two commonly used therapies on prostate cancer—radiation and total androgen blockade—induce predictable histologic changes in the tumor tissue. With the increasing use of post‐treatment biopsies to evaluate patients receiving radiation therapy and the use of neoadjuvant total androgen blockade before radical prostatectomy, recognition of these alterations is of considerable importance to pathologists. Additionally, the significance of the observed changes, as regards evaluating the therapeutic response, is of considerable interest. The purpose of this report is to review the current knowledge of these important issues. Cancer 1995;75:1837–41.

Original languageEnglish (US)
Pages (from-to)1837-1841
Number of pages5
JournalCancer
Volume75
Issue number7 S
DOIs
StatePublished - Apr 1 1995

Keywords

  • biopsy
  • hormone therapy
  • prostate gland
  • radiation
  • treatment effects

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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