Histone mediated gene activation in Toxoplasma gondii

William Sullivan, Mohamed Ali Hakimi

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

DNA processes, including transcriptional activation, are largely governed by histone modifications. For most eukaryotes, chromatin-remodeling machines have been identified that move, replace, or decorate histones. Recent studies have shed some important light on similar machinery operating in apicomplexan parasites, including the opportunistic pathogen Toxoplasma gondii. Here we present a synthesis of the current knowledge of histone mediated gene expression in Toxoplasma, particularly in the context of parasite differentiation.

Original languageEnglish
Pages (from-to)109-116
Number of pages8
JournalMolecular and Biochemical Parasitology
Volume148
Issue number2
DOIs
StatePublished - Aug 2006

Fingerprint

Toxoplasma
Histones
Transcriptional Activation
Parasites
Histone Code
Chromatin Assembly and Disassembly
Eukaryota
Gene Expression
Light
DNA

Keywords

  • Apicomplexa
  • Chromatin
  • Differentiation
  • Parasite
  • Transcription

ASJC Scopus subject areas

  • Molecular Biology
  • Parasitology

Cite this

Histone mediated gene activation in Toxoplasma gondii. / Sullivan, William; Hakimi, Mohamed Ali.

In: Molecular and Biochemical Parasitology, Vol. 148, No. 2, 08.2006, p. 109-116.

Research output: Contribution to journalArticle

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