Histoplasmosis

Lawrence J. Wheat, Marwan M. Azar, Nathan C. Bahr, Andrej Spec, Ryan Relich, Chadi Hage

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

Although histoplasmosis is highly endemic in certain regions of the Americas, disease may be seen globally and should not be overlooked in patients with unexplained pulmonary or systemic illnesses. Most patients exhibit pulmonary signs and symptoms, accompanied by radiographic abnormalities, which often are mistaken for community-acquired pneumonia caused by bacterial or viral agents. Once a diagnosis is considered, a panel of mycologic and non-culture-based assays is adequate to establish a diagnosis in a few days to a week in most patients. Once diagnosed, the treatment is highly effective even in immunocompromised patients.

Original languageEnglish (US)
Pages (from-to)207-227
Number of pages21
JournalInfectious Disease Clinics of North America
Volume30
Issue number1
DOIs
StatePublished - Mar 1 2016

Fingerprint

Histoplasmosis
Viral Pneumonia
Bacterial Pneumonia
Lung
Immunocompromised Host
Signs and Symptoms
Therapeutics

Keywords

  • Antibody
  • Antigen
  • Central nervous system
  • Disseminated
  • Histoplasma
  • Histoplasmosis
  • Pulmonary
  • Serology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Histoplasmosis. / Wheat, Lawrence J.; Azar, Marwan M.; Bahr, Nathan C.; Spec, Andrej; Relich, Ryan; Hage, Chadi.

In: Infectious Disease Clinics of North America, Vol. 30, No. 1, 01.03.2016, p. 207-227.

Research output: Contribution to journalArticle

Wheat, LJ, Azar, MM, Bahr, NC, Spec, A, Relich, R & Hage, C 2016, 'Histoplasmosis', Infectious Disease Clinics of North America, vol. 30, no. 1, pp. 207-227. https://doi.org/10.1016/j.idc.2015.10.009
Wheat, Lawrence J. ; Azar, Marwan M. ; Bahr, Nathan C. ; Spec, Andrej ; Relich, Ryan ; Hage, Chadi. / Histoplasmosis. In: Infectious Disease Clinics of North America. 2016 ; Vol. 30, No. 1. pp. 207-227.
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