Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Lindsey Egan, Patricia Connolly, L. Joseph Wheat, Deanna Fuller, Thomas E. Davis, Kenneth S. Knox, Chadi A. Hage

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

Original languageEnglish (US)
Pages (from-to)93-95
Number of pages3
JournalMedical Mycology
Volume46
Issue number1
DOIs
StatePublished - Feb 1 2008

Keywords

  • Antigen detection
  • Beta-glucan
  • Histoplasmosis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • veterinary(all)
  • Microbiology

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