Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Lindsey Egan, Patricia Connolly, L. Joseph Wheat, Deanna Fuller, Thomas Davis, Kenneth S. Knox, Chadi Hage

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

Original languageEnglish
Pages (from-to)93-95
Number of pages3
JournalMedical Mycology
Volume46
Issue number1
DOIs
StatePublished - Feb 2008

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histoplasmosis
Histoplasmosis
glucans
testing
Glucans
Mycoses
polyglucosan

Keywords

  • Antigen detection
  • Beta-glucan
  • Histoplasmosis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • veterinary(all)
  • Microbiology

Cite this

Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test. / Egan, Lindsey; Connolly, Patricia; Wheat, L. Joseph; Fuller, Deanna; Davis, Thomas; Knox, Kenneth S.; Hage, Chadi.

In: Medical Mycology, Vol. 46, No. 1, 02.2008, p. 93-95.

Research output: Contribution to journalArticle

Egan, Lindsey ; Connolly, Patricia ; Wheat, L. Joseph ; Fuller, Deanna ; Davis, Thomas ; Knox, Kenneth S. ; Hage, Chadi. / Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test. In: Medical Mycology. 2008 ; Vol. 46, No. 1. pp. 93-95.
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