Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder

Donald W. Black, Patrick Monahan, Janelle Gable, Nancee Blum, Gerard Clancy, Peggy Baker

Research output: Contribution to journalArticle

184 Citations (Scopus)

Abstract

Objective: The authors studied factors associated with short-term treatment response in 38 nondepressed subjects with DSM-III-R obsessive- compulsive disorder (OCD). Method: The subjects completed 12 weeks of treatment with paroxetine (N = 20), placebo (N = 8), or cognitive-behavioral therapy (N = 10). Clinician and self-rated measures were gathered at baseline, during treatment, and after treatment. Results: Seventeen (45%) subjects had 'much' or 'very much' improvement and achieved at least a 40% decrease in their total Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score. Responders had lower obsessive-compulsive scores on the Symptom Checklist 90- Revised, had a lower checking score on the Maudsley Obsessive-Compulsive Inventory, were less likely to have had prior drug therapy, and in general suffered more obsessive-compulsive symptoms. They were significantly less likely to have hoarding obsessions and corresponding compulsions. The latter finding was confirmed using multiple regression analysis. Conclusion: Hoarding is an important symptom that predicts poor treatment response in patients with OCD.

Original languageEnglish (US)
Pages (from-to)420-425
Number of pages6
JournalJournal of Clinical Psychiatry
Volume59
Issue number8
StatePublished - Aug 1998
Externally publishedYes

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Obsessive-Compulsive Disorder
Therapeutics
Obsessive Behavior
Paroxetine
Cognitive Therapy
Checklist
Diagnostic and Statistical Manual of Mental Disorders
Placebos
Regression Analysis
Hoarding
Drug Therapy
Equipment and Supplies

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder. / Black, Donald W.; Monahan, Patrick; Gable, Janelle; Blum, Nancee; Clancy, Gerard; Baker, Peggy.

In: Journal of Clinical Psychiatry, Vol. 59, No. 8, 08.1998, p. 420-425.

Research output: Contribution to journalArticle

Black, DW, Monahan, P, Gable, J, Blum, N, Clancy, G & Baker, P 1998, 'Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder', Journal of Clinical Psychiatry, vol. 59, no. 8, pp. 420-425.
Black, Donald W. ; Monahan, Patrick ; Gable, Janelle ; Blum, Nancee ; Clancy, Gerard ; Baker, Peggy. / Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder. In: Journal of Clinical Psychiatry. 1998 ; Vol. 59, No. 8. pp. 420-425.
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