Hodgkin's disease presenting as cholestatic hepatitis with prominent ductal injury

Suthat Liangpunsakul, Paul Kwo, George K. Koukoulis

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

In advanced stages of Hodgkin's disease, liver involvement is common. However, Hodgkin's disease mimicking cholestatic hepatitis at presentation is rare. We describe a patient with Hodgkin's disease who was initially considered to have acute cholestatic hepatitis. Liver biopsy demonstrated prominent bile duct injury associated with a florid inflammatory reaction. These changes may represent an early stage of ductal injury, subsequently leading to vanishing bile duct syndrome, a recently documented mechanism of cholestasis in Hodgkin's disease.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalEuropean Journal of Gastroenterology and Hepatology
Volume14
Issue number3
DOIs
StatePublished - Apr 9 2002

Keywords

  • Cholestatic jaundice
  • Hodgkin's disease
  • Vanishing bile duct syndrome

ASJC Scopus subject areas

  • Gastroenterology

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