Hypopharyngeal pH monitoring artifact in detection of laryngopharyngeal reflux

John M. Wo, Abdul Jabbar, Welby Winstead, Steve Goudy, Robert Cacchione, Jeff W. Allen

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Hypopharyngeal pH artifacts have been a concern in the detection of laryngopharyngeal reflux. Our purpose was to analyze and quantify artifacts from dual-sensor hypopharyngeal pH monitoring. In all, 42 hypopharyngeal and 58 esophageal pH studies were reviewed. Type 1 (out of range), type 2 (pH drift), and type 3 (isolated pH drop) artifacts were identified. The proportion of proximal-sensor pH drop to <4 that was artifactual was determined. The median number (range) of artifacts was 1 (0-17) and 2 (0-28) for hypopharyngeal and esophageal pH studies, respectively (P = NS). The median proportion of artifactual pH drop to <4 was 1% (0-84%) and 2% (0-74%) for hypopharyngeal and esophageal pH studies, respectively (P = NS). The diagnosis did not change in any patient after excluding pH artifacts. In all, 19% of the combined 2432 hypopharyngeal pH drops of <4 were artifacts. In conclusion, hypopharyngeal pH artifacts per study were uncommon but can be prominent in a few patients. One can identify these artifacts and exclude them from analysis.

Original languageEnglish (US)
Pages (from-to)2579-2585
Number of pages7
JournalDigestive diseases and sciences
Volume47
Issue number11
DOIs
StatePublished - Nov 1 2002
Externally publishedYes

Keywords

  • Ambulatory pH monitoring
  • GERD
  • Laryngopharyngeal reflux
  • pH artifacts

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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