Abstract
This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 304-307 |
| Number of pages | 4 |
| Journal | Human genomics |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jul 2009 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine
- Molecular Biology
- Genetics
- Drug Discovery
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Cite this
Moore, S. M., Liang, T., Graves, T. J., McCall, K. M., Carr, L. G., & Ehlers, C. L. (2009). Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. Human genomics, 3(4), 304-307. https://doi.org/10.1186/1479-7364-3-4-304