Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4.

Shelley M. Moore, Tiebing Liang, Tamara J. Graves, Kevin M. McCall, Lucinda G. Carr, Cindy L. Ehlers

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.

Original languageEnglish (US)
Pages (from-to)304-307
Number of pages4
JournalHuman Genomics
Volume3
Issue number4
StatePublished - Jul 2009
Externally publishedYes

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Aldehyde Dehydrogenase
Alleles
Gene Frequency
Alcoholism
aldehyde dehydrogenase 1

ASJC Scopus subject areas

  • Drug Discovery
  • Genetics
  • Molecular Biology
  • Molecular Medicine

Cite this

Moore, S. M., Liang, T., Graves, T. J., McCall, K. M., Carr, L. G., & Ehlers, C. L. (2009). Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. Human Genomics, 3(4), 304-307.

Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. / Moore, Shelley M.; Liang, Tiebing; Graves, Tamara J.; McCall, Kevin M.; Carr, Lucinda G.; Ehlers, Cindy L.

In: Human Genomics, Vol. 3, No. 4, 07.2009, p. 304-307.

Research output: Contribution to journalArticle

Moore, SM, Liang, T, Graves, TJ, McCall, KM, Carr, LG & Ehlers, CL 2009, 'Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4.', Human Genomics, vol. 3, no. 4, pp. 304-307.
Moore SM, Liang T, Graves TJ, McCall KM, Carr LG, Ehlers CL. Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. Human Genomics. 2009 Jul;3(4):304-307.
Moore, Shelley M. ; Liang, Tiebing ; Graves, Tamara J. ; McCall, Kevin M. ; Carr, Lucinda G. ; Ehlers, Cindy L. / Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. In: Human Genomics. 2009 ; Vol. 3, No. 4. pp. 304-307.
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