Abstract
This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 304-307 |
| Number of pages | 4 |
| Journal | Human Genomics |
| Volume | 3 |
| Issue number | 4 |
| State | Published - Jul 2009 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Drug Discovery
- Genetics
- Molecular Biology
- Molecular Medicine
Cite this
Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. / Moore, Shelley M.; Liang, Tiebing; Graves, Tamara J.; McCall, Kevin M.; Carr, Lucinda G.; Ehlers, Cindy L.
In: Human Genomics, Vol. 3, No. 4, 07.2009, p. 304-307.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4.
AU - Moore, Shelley M.
AU - Liang, Tiebing
AU - Graves, Tamara J.
AU - McCall, Kevin M.
AU - Carr, Lucinda G.
AU - Ehlers, Cindy L.
PY - 2009/7
Y1 - 2009/7
N2 - This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.
AB - This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.
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M3 - Article
VL - 3
SP - 304
EP - 307
JO - Human Genomics
JF - Human Genomics
SN - 1479-7364
IS - 4
ER -