Idiosyncratic drug-induced liver injury: A clinical update

Haripriya Maddur, Naga Chalasani

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Drug-induced liver injury (DILI) is a rare but potentially devastating adverse drug reaction. Its presentation can range from asymptomatic elevation in liver biochemistries to fulminant liver failure. Over the past decade, clinical and research interest in the field of idiosyncratic DILI has been intense, and several new findings have been reported. In this article, we provide an update on implicated agents, clinical features, outcomes, and the results of recently reported genetic studies.

Original languageEnglish (US)
Pages (from-to)65-71
Number of pages7
JournalCurrent gastroenterology reports
Volume13
Issue number1
DOIs
StatePublished - Feb 1 2011

Keywords

  • Drug-induced liver injury (DILI)
  • Drug-Induced Liver Injury Network (DILIN)
  • Genome-wide association studies

ASJC Scopus subject areas

  • Gastroenterology

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