Ifosfamide in testicular cancer

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Ifosfamide has demonstrated significant activity as salvage therapy in patients with testicular tumors refractory to cisplatin-containing induction chemotherapy regimens. Used as a single agent, ifosfamide produces objective responses in approximately 1 of 5 heavily pretreated patients failing to respond to any other agents. When ifosfamide is administered in combination with cisplatin and other agents, approximately 40% to 50% of pretreated patients with recurrent germ cell tumors achieve a complete remission. Studies currently under way should determine the optimal use of ifosfamide against testicular neoplasms, including its possible role as part of initial induction therapy.

Original languageEnglish (US)
Pages (from-to)2-5
Number of pages4
JournalSeminars in oncology
Volume17
Issue number2 SUPPL. 4
StatePublished - Apr 1990

ASJC Scopus subject areas

  • Hematology
  • Oncology

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