Ileocecal histoplasmosis simulating crohn disease in a patient with hyperimmunoglobulin e syndrome

Steven J. Steiner, Martin B. Kleiman, Mark R. Corkins, John C. Christenson, L. Joseph Wheat

Research output: Contribution to journalArticle

20 Scopus citations


We describe a 14-year-old girl with hyperimmunoglobulin E (Job) syndrome who presented with fatigue, abdominal pain, fever, and weight loss. Endoscopic examination of the terminal ileum revealed ulceration, edema, and erythema. Histopathologic findings of the terminal ileum demonstrated intracellular yeast forms compatible with Histoplasma capsulatum. The patient was treated with oral itraconazole and had a rapid and complete response.

Original languageEnglish (US)
Pages (from-to)744-746
Number of pages3
JournalPediatric Infectious Disease Journal
Issue number8
StatePublished - Aug 2009



  • Crohn disease
  • Histoplasmosis
  • Job syndrome
  • Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

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