Imaging cortical anatomy by high-resolution MR at 3.0T: Detection of the stripe of Gennari in visual area 17

Emmanuel L. Barbier, Sean Marrett, Adrian Danek, Alexander Vortmeyer, Peter Van Gelderen, Jeff Duyn, Peter Bandettini, Jordan Grafman, Alan P. Koretsky

Research output: Contribution to journalArticle

119 Citations (Scopus)

Abstract

The brain can be parcellated into numerous anatomical and functional subunits. The classic work by Brodmann (Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Leipzig: Barth; 1909) identified areas of the cerebral cortex based on histological differences. An alternative to his cytoarchitectonic approach is the myeloarchitectonic approach. MRI has excellent white/gray matter contrast in the brain due to the presence of myelin, and thus seems uniquely suited for in vivo studies of cortical myeloarchitecture. Here it is demonstrated that the stripe or stria of Gennari can be consistently detected in human occipital cortex. T1-weighted images obtained at 3T from six of 10 normal volunteers, with resolutions of 350 × 350 × 600 μ, clearly demonstrate this myelin-rich intracortical layer. It is concluded that the striate cortex (area 17 of Brodmann) of the human brain can be delineated in vivo on T1-weighted images, potentially enabling detection of specific cortical boundaries within individual brains.

Original languageEnglish (US)
Pages (from-to)735-738
Number of pages4
JournalMagnetic Resonance in Medicine
Volume48
Issue number4
DOIs
StatePublished - Oct 1 2002
Externally publishedYes

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Anatomy
Brain
Myelin Sheath
Occipital Lobe
Visual Cortex
Cerebral Cortex
Healthy Volunteers

Keywords

  • Area V1
  • Brain maps
  • Cortical architecture
  • Human
  • Myelin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Imaging cortical anatomy by high-resolution MR at 3.0T : Detection of the stripe of Gennari in visual area 17. / Barbier, Emmanuel L.; Marrett, Sean; Danek, Adrian; Vortmeyer, Alexander; Van Gelderen, Peter; Duyn, Jeff; Bandettini, Peter; Grafman, Jordan; Koretsky, Alan P.

In: Magnetic Resonance in Medicine, Vol. 48, No. 4, 01.10.2002, p. 735-738.

Research output: Contribution to journalArticle

Barbier, EL, Marrett, S, Danek, A, Vortmeyer, A, Van Gelderen, P, Duyn, J, Bandettini, P, Grafman, J & Koretsky, AP 2002, 'Imaging cortical anatomy by high-resolution MR at 3.0T: Detection of the stripe of Gennari in visual area 17', Magnetic Resonance in Medicine, vol. 48, no. 4, pp. 735-738. https://doi.org/10.1002/mrm.10255
Barbier, Emmanuel L. ; Marrett, Sean ; Danek, Adrian ; Vortmeyer, Alexander ; Van Gelderen, Peter ; Duyn, Jeff ; Bandettini, Peter ; Grafman, Jordan ; Koretsky, Alan P. / Imaging cortical anatomy by high-resolution MR at 3.0T : Detection of the stripe of Gennari in visual area 17. In: Magnetic Resonance in Medicine. 2002 ; Vol. 48, No. 4. pp. 735-738.
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