Imaging gene expression

Rajesh Kher, Robert L. Bacallao

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Genome-wide sequencing and increasing use of microarrays has resulted in the identification of a large number of new genes which may have important functional roles in development and onset of disease. Classical approaches in gene expression studies fall short in providing information about cellular localization of these genes and their relative levels of expression in tissues. Rapid determination of gene expression can be achieved with in situ methods of localization of gene expression in combination with recent developments in imaging technology.

Original languageEnglish (US)
Pages (from-to)e75-e80
JournalNephron - Experimental Nephrology
Volume103
Issue number2
DOIs
StatePublished - Mar 1 2006

Keywords

  • Confocal microscopy
  • Gene expression
  • In situ hybridization
  • In situ reverse transcriptase PCR

ASJC Scopus subject areas

  • Nephrology

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