Immune evasion of the CD1d/NKT cell axis

Randy R. Brutkiewicz, Laura Yunes-Medina, Jianyun Liu

Research output: Contribution to journalReview article

2 Scopus citations


Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.

Original languageEnglish (US)
Pages (from-to)87-92
Number of pages6
JournalCurrent Opinion in Immunology
StatePublished - Jun 2018

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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