Immunohistology of Peyer's patches in the dog

Harm HogenEsch, Peter J. Felsburg

Research output: Contribution to journalArticle

28 Scopus citations


Canine Peyer's patches were examined by light microscopy and immunohistochemistry for possible variations depending on the location within the small intestine and for similarities and dissimilarities to PPs from other species. The duodenal and jejunal PPs were characterized by relatively large domes and interfollicular areas. In contrast, the ileal PP had small domes and poorly developed interfollicular areas and very large follicles. T cells were found in the interfollicular area and corona and in lesser numbers in the dome and germinal centers. The ileal PP contained far fewer T cells than the proximal PPs. Domes of canine PPs contained some cytoplasmic IgA+ (cIgA+) and many cIgG+ cells. Peanut agglutinin (PNA) stained germinal center cells in a selective but not-uniform way and did not stain T cells.

Original languageEnglish (US)
Pages (from-to)147-160
Number of pages14
JournalVeterinary Immunology and Immunopathology
Issue number2-3
StatePublished - Jan 15 1992
Externally publishedYes

ASJC Scopus subject areas

  • Immunology
  • veterinary(all)

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