Impact of dependent left truncation in semiparametric competing risks methods: A simulation study

Giorgos Bakoyannis, Giota Touloumi

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

In this study, we investigated the robustness of the methods that account for independent left truncation when applied to competing risks settings with dependent left truncation. We specifically focused on the methods for the proportional cause-specific hazards model and the Fine–Gray model. Simulation experiments showed that these methods are not in general robust against dependent left truncation. The magnitude of the bias was analogous to the strength of the association between left truncation and failure times, the effect of the covariate on the competing cause of failure, and the baseline hazard of left truncation time.

Original languageEnglish (US)
Pages (from-to)2025-2042
Number of pages18
JournalCommunications in Statistics: Simulation and Computation
Volume46
Issue number3
DOIs
StatePublished - Mar 16 2017

Keywords

  • Cause-specific hazards model
  • Competing risks
  • Fine–Gray model
  • Late entry
  • Left truncation

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation

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