Impact of pain severity and location on health-related quality of life

Dennis C. Ang, Kurt Kroenke, Colleen A. McHorney

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Despite evidence that persistent pain affects well-being, little is known about the relationship of the location of pain to psychological and functional well-being. To determine whether patients with musculoskeletal disorders (MSD) are more likely to be depressed and functionally disabled compared to patients with pain at other sites, we conducted a secondary data analysis of the Medical Outcome Study - an observational study of adult outpatients with chronic medical conditions. Of the 3,360 patients who completed the baseline assessment, 1,237 (36.8%) had MSD and 2,123 (63.2%) had no MSD. Among patients in the MSD group, 84.5% reported ≥mild pain as compared to 70% in the no MSD. In multivariate analyses, MSD patients were more likely than non-MSD patients to be depressed (β coefficient = -1.9, p = 0.008) and functionally disabled (β coefficient = -4.4, p < 0.0001). However, the impact of MSD was eliminated after controlling for pain severity. Regardless of the location of pain, pain severity appears to be an important correlate of functional status, both mental and physical.

Original languageEnglish
Pages (from-to)567-572
Number of pages6
JournalRheumatology International
Volume26
Issue number6
DOIs
StatePublished - Apr 2006

Fingerprint

Quality of Life
Pain
Observational Studies
Outpatients
Multivariate Analysis
Outcome Assessment (Health Care)
Psychology

Keywords

  • Chronic pain
  • Depression
  • Musculoskeletal disorders
  • Observational study
  • Physical function

ASJC Scopus subject areas

  • Rheumatology

Cite this

Impact of pain severity and location on health-related quality of life. / Ang, Dennis C.; Kroenke, Kurt; McHorney, Colleen A.

In: Rheumatology International, Vol. 26, No. 6, 04.2006, p. 567-572.

Research output: Contribution to journalArticle

Ang, Dennis C. ; Kroenke, Kurt ; McHorney, Colleen A. / Impact of pain severity and location on health-related quality of life. In: Rheumatology International. 2006 ; Vol. 26, No. 6. pp. 567-572.
@article{aa600deb4c814e66aab4b60147688568,
title = "Impact of pain severity and location on health-related quality of life",
abstract = "Despite evidence that persistent pain affects well-being, little is known about the relationship of the location of pain to psychological and functional well-being. To determine whether patients with musculoskeletal disorders (MSD) are more likely to be depressed and functionally disabled compared to patients with pain at other sites, we conducted a secondary data analysis of the Medical Outcome Study - an observational study of adult outpatients with chronic medical conditions. Of the 3,360 patients who completed the baseline assessment, 1,237 (36.8{\%}) had MSD and 2,123 (63.2{\%}) had no MSD. Among patients in the MSD group, 84.5{\%} reported ≥mild pain as compared to 70{\%} in the no MSD. In multivariate analyses, MSD patients were more likely than non-MSD patients to be depressed (β coefficient = -1.9, p = 0.008) and functionally disabled (β coefficient = -4.4, p < 0.0001). However, the impact of MSD was eliminated after controlling for pain severity. Regardless of the location of pain, pain severity appears to be an important correlate of functional status, both mental and physical.",
keywords = "Chronic pain, Depression, Musculoskeletal disorders, Observational study, Physical function",
author = "Ang, {Dennis C.} and Kurt Kroenke and McHorney, {Colleen A.}",
year = "2006",
month = "4",
doi = "10.1007/s00296-005-0025-z",
language = "English",
volume = "26",
pages = "567--572",
journal = "Rheumatology International",
issn = "0172-8172",
publisher = "Springer Verlag",
number = "6",

}

TY - JOUR

T1 - Impact of pain severity and location on health-related quality of life

AU - Ang, Dennis C.

AU - Kroenke, Kurt

AU - McHorney, Colleen A.

PY - 2006/4

Y1 - 2006/4

N2 - Despite evidence that persistent pain affects well-being, little is known about the relationship of the location of pain to psychological and functional well-being. To determine whether patients with musculoskeletal disorders (MSD) are more likely to be depressed and functionally disabled compared to patients with pain at other sites, we conducted a secondary data analysis of the Medical Outcome Study - an observational study of adult outpatients with chronic medical conditions. Of the 3,360 patients who completed the baseline assessment, 1,237 (36.8%) had MSD and 2,123 (63.2%) had no MSD. Among patients in the MSD group, 84.5% reported ≥mild pain as compared to 70% in the no MSD. In multivariate analyses, MSD patients were more likely than non-MSD patients to be depressed (β coefficient = -1.9, p = 0.008) and functionally disabled (β coefficient = -4.4, p < 0.0001). However, the impact of MSD was eliminated after controlling for pain severity. Regardless of the location of pain, pain severity appears to be an important correlate of functional status, both mental and physical.

AB - Despite evidence that persistent pain affects well-being, little is known about the relationship of the location of pain to psychological and functional well-being. To determine whether patients with musculoskeletal disorders (MSD) are more likely to be depressed and functionally disabled compared to patients with pain at other sites, we conducted a secondary data analysis of the Medical Outcome Study - an observational study of adult outpatients with chronic medical conditions. Of the 3,360 patients who completed the baseline assessment, 1,237 (36.8%) had MSD and 2,123 (63.2%) had no MSD. Among patients in the MSD group, 84.5% reported ≥mild pain as compared to 70% in the no MSD. In multivariate analyses, MSD patients were more likely than non-MSD patients to be depressed (β coefficient = -1.9, p = 0.008) and functionally disabled (β coefficient = -4.4, p < 0.0001). However, the impact of MSD was eliminated after controlling for pain severity. Regardless of the location of pain, pain severity appears to be an important correlate of functional status, both mental and physical.

KW - Chronic pain

KW - Depression

KW - Musculoskeletal disorders

KW - Observational study

KW - Physical function

UR - http://www.scopus.com/inward/record.url?scp=33645341716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645341716&partnerID=8YFLogxK

U2 - 10.1007/s00296-005-0025-z

DO - 10.1007/s00296-005-0025-z

M3 - Article

VL - 26

SP - 567

EP - 572

JO - Rheumatology International

JF - Rheumatology International

SN - 0172-8172

IS - 6

ER -