Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research

Andrew Arenson; Ludmila Bakhireva; Tina Chambers; Christina Deximo; Tatiana Foroud; Joseph Jacobson; Sandra Jacobson; Kenneth Lyons Jones; Sarah Mattson; Philip May; Elizabeth Moore; Kimberly Ogle; Edward Riley; Luther Robinson; Jeffrey Rogers; Ann Streissguth; Michel Tavares; Joseph Urbanski; Helen Yezerets; Craig A. Stewart

doi:10.1007/978-3-540-69968-2_4

Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research

Andrew Arenson, Ludmila Bakhireva, Tina Chambers, Christina Deximo, Tatiana Foroud, Joseph Jacobson, Sandra Jacobson, Kenneth Lyons Jones, Sarah Mattson, Philip May, Elizabeth Moore, Kimberly Ogle, Edward Riley, Luther Robinson, Jeffrey Rogers, Ann Streissguth, Michel Tavares, Joseph Urbanski, Helen Yezerets, Craig A. Stewart

Medical & Molecular Genetics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We implemented a distributed system for management of data for an international collaboration studying Fetal Alcohol Spectrum Disorders (FASD). Subject privacy was protected, researchers without dependable Internet access were accommodated, and researchers' data were shared globally. Data dictionaries codified the nature of the data being integrated, data compliance was assured through multiple consistency checks, and recovery systems provided a secure, robust, persistent repository. The system enabled new types of science to be done, using distributed technologies that are expedient for current needs while taking useful steps towards integrating the system in a future grid-based cyberinfrastructure. The distributed architecture, verification steps, and data dictionaries suggest general strategies for researchers involved in collaborative studies, particularly where data must be de-identified before being shared. The system met both the collaboration's needs and the NIH Roadmap's goal of wide access to databases that are robust and adaptable to researchers' needs.

Original language	English (US)
Title of host publication	Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings
Publisher	Springer Verlag
Pages	33-44
Number of pages	12
ISBN (Print)	3540698418, 9783540698418
DOIs	https://doi.org/10.1007/978-3-540-69968-2_4
State	Published - 2007
Event	Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006 - Eilat, Israel Duration: Jan 21 2007 → Jan 21 2007

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	4360 LNBI
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006
Country	Israel
City	Eilat
Period	1/21/07 → 1/21/07

Keywords

Data dictionary
Distributed computing
Fetal alcohol spectrum disorders
Repository

ASJC Scopus subject areas

Computer Science(all)
Biochemistry, Genetics and Molecular Biology(all)
Theoretical Computer Science

Access to Document

10.1007/978-3-540-69968-2_4

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Cite this

Arenson, A., Bakhireva, L., Chambers, T., Deximo, C., Foroud, T., Jacobson, J., Jacobson, S., Jones, K. L., Mattson, S., May, P., Moore, E., Ogle, K., Riley, E., Robinson, L., Rogers, J., Streissguth, A., Tavares, M., Urbanski, J., Yezerets, H., & Stewart, C. A. (2007). Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research. In Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings (pp. 33-44). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4360 LNBI). Springer Verlag. https://doi.org/10.1007/978-3-540-69968-2_4

Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research. / Arenson, Andrew; Bakhireva, Ludmila; Chambers, Tina; Deximo, Christina; Foroud, Tatiana; Jacobson, Joseph; Jacobson, Sandra; Jones, Kenneth Lyons; Mattson, Sarah; May, Philip; Moore, Elizabeth; Ogle, Kimberly; Riley, Edward; Robinson, Luther; Rogers, Jeffrey; Streissguth, Ann; Tavares, Michel; Urbanski, Joseph; Yezerets, Helen; Stewart, Craig A.

Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings. Springer Verlag, 2007. p. 33-44 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4360 LNBI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Arenson, A, Bakhireva, L, Chambers, T, Deximo, C, Foroud, T, Jacobson, J, Jacobson, S, Jones, KL, Mattson, S, May, P, Moore, E, Ogle, K, Riley, E, Robinson, L, Rogers, J, Streissguth, A, Tavares, M, Urbanski, J, Yezerets, H & Stewart, CA 2007, Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research. in Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 4360 LNBI, Springer Verlag, pp. 33-44, Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Eilat, Israel, 1/21/07. https://doi.org/10.1007/978-3-540-69968-2_4

Arenson A, Bakhireva L, Chambers T, Deximo C, Foroud T, Jacobson J et al. Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research. In Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings. Springer Verlag. 2007. p. 33-44. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-540-69968-2_4

Arenson, Andrew ; Bakhireva, Ludmila ; Chambers, Tina ; Deximo, Christina ; Foroud, Tatiana ; Jacobson, Joseph ; Jacobson, Sandra ; Jones, Kenneth Lyons ; Mattson, Sarah ; May, Philip ; Moore, Elizabeth ; Ogle, Kimberly ; Riley, Edward ; Robinson, Luther ; Rogers, Jeffrey ; Streissguth, Ann ; Tavares, Michel ; Urbanski, Joseph ; Yezerets, Helen ; Stewart, Craig A. / Implementation of a distributed architecture for managing collection and dissemination of data for fetal alcohol spectrum disorders research. Distributed, High-Performance and Grid Computing in Computational Biology International Workshop, GCCB 2006, Proceedings. Springer Verlag, 2007. pp. 33-44 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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