Importance of location and timing of electrical stimuli in terminating sustained functional reentry in isolated swine ventricular tissues

Evidence in support of a small reentrant circuit

Kamyar Kamjoo, Takumi Uchida, Takanori Ikeda, Michael C. Fishbein, Alan Garfinkel, James N. Weiss, Hrayr S. Karagueuzian, Peng-Sheng Chen

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Background: In excitable chemical media, a spiral wave is formed by reentrant excitation around a core and normal propagation away from the core. Whether or not this applies to cardiac muscle is unknown. Methods and Results: In six isolated swine ventricular slices, we induced sustained episodes of functional reentry with a stationary core. A train of stimuli applied away from the core (7- to 8-mm distance) and near the core (within 1.6 mm) terminated 5 of 24 and 14 of 17 episodes of reentry, respectively (P

Original languageEnglish (US)
Pages (from-to)2048-2060
Number of pages13
JournalCirculation
Volume96
Issue number6
StatePublished - Sep 16 1997
Externally publishedYes

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Myocardium
Swine

Keywords

  • Defibrillation
  • Electrophysiology
  • Mapping
  • Pacing
  • Waves

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Importance of location and timing of electrical stimuli in terminating sustained functional reentry in isolated swine ventricular tissues : Evidence in support of a small reentrant circuit. / Kamjoo, Kamyar; Uchida, Takumi; Ikeda, Takanori; Fishbein, Michael C.; Garfinkel, Alan; Weiss, James N.; Karagueuzian, Hrayr S.; Chen, Peng-Sheng.

In: Circulation, Vol. 96, No. 6, 16.09.1997, p. 2048-2060.

Research output: Contribution to journalArticle

Kamjoo, Kamyar ; Uchida, Takumi ; Ikeda, Takanori ; Fishbein, Michael C. ; Garfinkel, Alan ; Weiss, James N. ; Karagueuzian, Hrayr S. ; Chen, Peng-Sheng. / Importance of location and timing of electrical stimuli in terminating sustained functional reentry in isolated swine ventricular tissues : Evidence in support of a small reentrant circuit. In: Circulation. 1997 ; Vol. 96, No. 6. pp. 2048-2060.
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