Combination chemotherapy with platinum + vinblastine + bleomycin in disseminated testicular cancer has been highly successful, producing 28 complete (72%) and 11 partial (28%) remissions in 39 evaluable patients. Furthermore, an additional 5 patients have been rendered disease-free by surgical removal of residual disease, making the effective disease-free status 85%. 32 of these patients remain alive, and 25 remain alive and disease-free from 3+ to 24+ mths. Despite the significant toxicity during the first 12 wks of this therapeutic regimen, it was usually manageable and maintainance therapy produced minimal toxicity. This regimen is considered to be a major advance in the management of patients with disseminated testicular cancer.
|Title of host publication||J.CLIN.HEMATOL.ONCOL.|
|Number of pages||10|
|State||Published - 1977|
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