Improved chemotherapy in disseminated testicular cancer

Lawrence Einhorn, B. Furnas

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations

Abstract

Combination chemotherapy with platinum + vinblastine + bleomycin in disseminated testicular cancer has been highly successful, producing 28 complete (72%) and 11 partial (28%) remissions in 39 evaluable patients. Furthermore, an additional 5 patients have been rendered disease-free by surgical removal of residual disease, making the effective disease-free status 85%. 32 of these patients remain alive, and 25 remain alive and disease-free from 3+ to 24+ mths. Despite the significant toxicity during the first 12 wks of this therapeutic regimen, it was usually manageable and maintainance therapy produced minimal toxicity. This regimen is considered to be a major advance in the management of patients with disseminated testicular cancer.

Original languageEnglish
Title of host publicationJ.CLIN.HEMATOL.ONCOL.
Pages662-671
Number of pages10
Volume7
Edition2
StatePublished - 1977

ASJC Scopus subject areas

  • Medicine(all)

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    Einhorn, L., & Furnas, B. (1977). Improved chemotherapy in disseminated testicular cancer. In J.CLIN.HEMATOL.ONCOL. (2 ed., Vol. 7, pp. 662-671)