In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion

Samira Helena João-Souza, Sávio José C. Bezerra, Patrícia Moreira de Freitas, Nelson B. de Lima, Ana Cecília Corrêa Aranha, Anderson Hara, Taís Scaramucci

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm of fluoride), sodium fluoride + stannous chloride (F + Sn: 225 ppm of fluoride + 800 ppm of stannous), sodium fluoride + stannous chloride + sodium linear polyphosphate (F + Sn + LPP: 225 ppm of fluoride + 800 ppm of stannous + 2% of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. Methods In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2 h of salivary pellicle formation with the appliance in situ, followed by 2 min extra-oral immersion in 1% citric acid (pH 2.4), 6x/day, with 90 min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α = 0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n = 3). Results C (mean SL ± standard-deviation: 5.97 ± 1.70) and F (5.36 ± 1.59) showed the highest SL, with no significant difference between them (p > 0.05). F + Sn (2.68 ± 1.62) and F + Sn + LPP (2.10 ± 0.95) did not differ from each other (p > 0.05), but presented lower SL than the other groups (P < 0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F + Sn and F + Sn + LPP. Conclusions Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. Clinical significance Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.

Original languageEnglish (US)
Pages (from-to)30-35
Number of pages6
JournalJournal of Dentistry
Volume63
DOIs
StatePublished - Aug 1 2017

Fingerprint

Tin Polyphosphates
Sodium Fluoride
Dental Enamel
Fluorides
Polyphosphates
Tin Fluorides
Sodium
Sodium Chloride
Dental Pellicle
X-Rays
Apatites
Immersion
Saliva
Citric Acid
Volunteers
Analysis of Variance
Clinical Trials

Keywords

  • Enamel
  • Erosion
  • Fluoride
  • Phosphate polymer
  • Stannous chloride

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

João-Souza, S. H., Bezerra, S. J. C., de Freitas, P. M., de Lima, N. B., Aranha, A. C. C., Hara, A., & Scaramucci, T. (2017). In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion. Journal of Dentistry, 63, 30-35. https://doi.org/10.1016/j.jdent.2017.05.014

In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion. / João-Souza, Samira Helena; Bezerra, Sávio José C.; de Freitas, Patrícia Moreira; de Lima, Nelson B.; Aranha, Ana Cecília Corrêa; Hara, Anderson; Scaramucci, Taís.

In: Journal of Dentistry, Vol. 63, 01.08.2017, p. 30-35.

Research output: Contribution to journalArticle

João-Souza, SH, Bezerra, SJC, de Freitas, PM, de Lima, NB, Aranha, ACC, Hara, A & Scaramucci, T 2017, 'In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion', Journal of Dentistry, vol. 63, pp. 30-35. https://doi.org/10.1016/j.jdent.2017.05.014
João-Souza, Samira Helena ; Bezerra, Sávio José C. ; de Freitas, Patrícia Moreira ; de Lima, Nelson B. ; Aranha, Ana Cecília Corrêa ; Hara, Anderson ; Scaramucci, Taís. / In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion. In: Journal of Dentistry. 2017 ; Vol. 63. pp. 30-35.
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abstract = "Objective To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm of fluoride), sodium fluoride + stannous chloride (F + Sn: 225 ppm of fluoride + 800 ppm of stannous), sodium fluoride + stannous chloride + sodium linear polyphosphate (F + Sn + LPP: 225 ppm of fluoride + 800 ppm of stannous + 2{\%} of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. Methods In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2 h of salivary pellicle formation with the appliance in situ, followed by 2 min extra-oral immersion in 1{\%} citric acid (pH 2.4), 6x/day, with 90 min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α = 0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n = 3). Results C (mean SL ± standard-deviation: 5.97 ± 1.70) and F (5.36 ± 1.59) showed the highest SL, with no significant difference between them (p > 0.05). F + Sn (2.68 ± 1.62) and F + Sn + LPP (2.10 ± 0.95) did not differ from each other (p > 0.05), but presented lower SL than the other groups (P < 0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F + Sn and F + Sn + LPP. Conclusions Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. Clinical significance Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.",
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T1 - In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion

AU - João-Souza, Samira Helena

AU - Bezerra, Sávio José C.

AU - de Freitas, Patrícia Moreira

AU - de Lima, Nelson B.

AU - Aranha, Ana Cecília Corrêa

AU - Hara, Anderson

AU - Scaramucci, Taís

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Objective To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm of fluoride), sodium fluoride + stannous chloride (F + Sn: 225 ppm of fluoride + 800 ppm of stannous), sodium fluoride + stannous chloride + sodium linear polyphosphate (F + Sn + LPP: 225 ppm of fluoride + 800 ppm of stannous + 2% of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. Methods In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2 h of salivary pellicle formation with the appliance in situ, followed by 2 min extra-oral immersion in 1% citric acid (pH 2.4), 6x/day, with 90 min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α = 0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n = 3). Results C (mean SL ± standard-deviation: 5.97 ± 1.70) and F (5.36 ± 1.59) showed the highest SL, with no significant difference between them (p > 0.05). F + Sn (2.68 ± 1.62) and F + Sn + LPP (2.10 ± 0.95) did not differ from each other (p > 0.05), but presented lower SL than the other groups (P < 0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F + Sn and F + Sn + LPP. Conclusions Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. Clinical significance Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.

AB - Objective To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm of fluoride), sodium fluoride + stannous chloride (F + Sn: 225 ppm of fluoride + 800 ppm of stannous), sodium fluoride + stannous chloride + sodium linear polyphosphate (F + Sn + LPP: 225 ppm of fluoride + 800 ppm of stannous + 2% of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. Methods In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2 h of salivary pellicle formation with the appliance in situ, followed by 2 min extra-oral immersion in 1% citric acid (pH 2.4), 6x/day, with 90 min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α = 0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n = 3). Results C (mean SL ± standard-deviation: 5.97 ± 1.70) and F (5.36 ± 1.59) showed the highest SL, with no significant difference between them (p > 0.05). F + Sn (2.68 ± 1.62) and F + Sn + LPP (2.10 ± 0.95) did not differ from each other (p > 0.05), but presented lower SL than the other groups (P < 0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F + Sn and F + Sn + LPP. Conclusions Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. Clinical significance Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.

KW - Enamel

KW - Erosion

KW - Fluoride

KW - Phosphate polymer

KW - Stannous chloride

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