In Vitro Activities of Moxifloxacin against 900 Aerobic and Anaerobic Surgical Isolates from Patients with Intra-Abdominal and Diabetic Foot Infections

Charles E. Edmiston, Candace J. Krepel, Gary R. Seabrook, Lewis R. Somberg, Atilla Nakeeb, Robert A. Cambria, Jonathan B. Towne

Research output: Contribution to journalArticle

78 Scopus citations

Abstract

The in vitro activities of moxifloxacin, ciprofloxacin, levofloxacin, gatifloxacin, imipenem, piperacillin-tazobactam, clindamycin, and metronidazole against 900 surgical isolates were determined using NCCLS testing methods. Moxifloxacin exhibited good to excellent antimicrobial activity against most aerobic (90.8%) and anaerobic (97.1%) microorganisms, suggesting that it may be effective for the treatment of polymicrobial surgical infections.

Original languageEnglish (US)
Pages (from-to)1012-1016
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number3
DOIs
StatePublished - Mar 2004

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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