In Vitro Activities of Moxifloxacin against 900 Aerobic and Anaerobic Surgical Isolates from Patients with Intra-Abdominal and Diabetic Foot Infections

Charles E. Edmiston, Candace J. Krepel, Gary R. Seabrook, Lewis R. Somberg, Attila Nakeeb, Robert A. Cambria, Jonathan B. Towne

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

The in vitro activities of moxifloxacin, ciprofloxacin, levofloxacin, gatifloxacin, imipenem, piperacillin-tazobactam, clindamycin, and metronidazole against 900 surgical isolates were determined using NCCLS testing methods. Moxifloxacin exhibited good to excellent antimicrobial activity against most aerobic (90.8%) and anaerobic (97.1%) microorganisms, suggesting that it may be effective for the treatment of polymicrobial surgical infections.

Original languageEnglish (US)
Pages (from-to)1012-1016
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number3
DOIs
StatePublished - Mar 2004
Externally publishedYes

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Diabetic Foot
Levofloxacin
Clindamycin
Imipenem
Metronidazole
Ciprofloxacin
Infection
Coinfection
moxifloxacin
In Vitro Techniques
Therapeutics
gatifloxacin
tazobactam drug combination piperacillin

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

In Vitro Activities of Moxifloxacin against 900 Aerobic and Anaerobic Surgical Isolates from Patients with Intra-Abdominal and Diabetic Foot Infections. / Edmiston, Charles E.; Krepel, Candace J.; Seabrook, Gary R.; Somberg, Lewis R.; Nakeeb, Attila; Cambria, Robert A.; Towne, Jonathan B.

In: Antimicrobial Agents and Chemotherapy, Vol. 48, No. 3, 03.2004, p. 1012-1016.

Research output: Contribution to journalArticle

Edmiston, Charles E. ; Krepel, Candace J. ; Seabrook, Gary R. ; Somberg, Lewis R. ; Nakeeb, Attila ; Cambria, Robert A. ; Towne, Jonathan B. / In Vitro Activities of Moxifloxacin against 900 Aerobic and Anaerobic Surgical Isolates from Patients with Intra-Abdominal and Diabetic Foot Infections. In: Antimicrobial Agents and Chemotherapy. 2004 ; Vol. 48, No. 3. pp. 1012-1016.
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