In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr

Frank A. Müller, Marco C. Bottino, Lenka Müller, Vinicius A R Henriques, Ulrich Lohbauer, Ana Helena A Bressiani, José C. Bressiani

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Objectives: Titanium alloys are considered the material of choice when used as endosteal part of implants. However, they are not able to bond directly to bone. The objective of this study was to suggest a chemical surface treatment for Ti-13Nb-13Zr to initiate the formation of hydroxy carbonated apatite (HCA) during in vitro bioactivity tests in simulated body fluid (SBF). Methods: Titanium, niobium, and zirconium hydride powders were blended, compacted and sintered. Sintered Ti-13Nb-13Zr samples were etched in HCl, H3PO4, and in a mixture of HF + HNO3, respectively, and subsequently pretreated in NaOH. The influence of acid etching conditions on the microstructure of the Ti-13Nb-13Zr alloys as well as on the rate of HCA formation was evaluated using SEM-EDS, FTIR, and gravimetric analyses. Results: Sintered Ti-13Nb-13Zr alloys consist of a Widmannstätten (α + β) microstructure. Exposure of chemically etched and NaOH activated samples to SBF for 1 week leads to the formation of a HCA layer on the surface of HCl as well as H3PO4 treated samples. No HCA formation was found on HNO3 treated samples. After 2 weeks in SBF the mass increase, that can be correlated to the HCA formation rate, was the highest for HCl pretreated samples (2.4 mg/cm2) followed by H3PO4 (0.8 mg/cm2) and HNO3 pretreated ones (0.2 mg/cm2). Significance: Since the in vitro HCA formation from SBF is generally accepted as a typical feature for bioactive materials, it is supposed that HCl etching with subsequent NaOH treatment might enhance the in vivo bone-bonding ability of Ti-13Nb-13Zr.

Original languageEnglish (US)
Pages (from-to)50-56
Number of pages7
JournalDental Materials
Volume24
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

Fingerprint

Apatites
Apatite
Body fluids
Body Fluids
Titanium
Etching
Bone
Niobium
Bone and Bones
Microstructure
Fourier Transform Infrared Spectroscopy
Bioactivity
Titanium alloys
Zirconium
Hydrides
Powders
Surface treatment
In Vitro Techniques
Energy dispersive spectroscopy
Scanning electron microscopy

Keywords

  • Bioactivity
  • Powder metallurgy
  • Simulated body fluid
  • Surface modification
  • Titanium alloys

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Müller, F. A., Bottino, M. C., Müller, L., Henriques, V. A. R., Lohbauer, U., Bressiani, A. H. A., & Bressiani, J. C. (2008). In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr. Dental Materials, 24(1), 50-56. https://doi.org/10.1016/j.dental.2007.02.005

In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr. / Müller, Frank A.; Bottino, Marco C.; Müller, Lenka; Henriques, Vinicius A R; Lohbauer, Ulrich; Bressiani, Ana Helena A; Bressiani, José C.

In: Dental Materials, Vol. 24, No. 1, 01.2008, p. 50-56.

Research output: Contribution to journalArticle

Müller, FA, Bottino, MC, Müller, L, Henriques, VAR, Lohbauer, U, Bressiani, AHA & Bressiani, JC 2008, 'In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr', Dental Materials, vol. 24, no. 1, pp. 50-56. https://doi.org/10.1016/j.dental.2007.02.005
Müller FA, Bottino MC, Müller L, Henriques VAR, Lohbauer U, Bressiani AHA et al. In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr. Dental Materials. 2008 Jan;24(1):50-56. https://doi.org/10.1016/j.dental.2007.02.005
Müller, Frank A. ; Bottino, Marco C. ; Müller, Lenka ; Henriques, Vinicius A R ; Lohbauer, Ulrich ; Bressiani, Ana Helena A ; Bressiani, José C. / In vitro apatite formation on chemically treated (P/M) Ti-13Nb-13Zr. In: Dental Materials. 2008 ; Vol. 24, No. 1. pp. 50-56.
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abstract = "Objectives: Titanium alloys are considered the material of choice when used as endosteal part of implants. However, they are not able to bond directly to bone. The objective of this study was to suggest a chemical surface treatment for Ti-13Nb-13Zr to initiate the formation of hydroxy carbonated apatite (HCA) during in vitro bioactivity tests in simulated body fluid (SBF). Methods: Titanium, niobium, and zirconium hydride powders were blended, compacted and sintered. Sintered Ti-13Nb-13Zr samples were etched in HCl, H3PO4, and in a mixture of HF + HNO3, respectively, and subsequently pretreated in NaOH. The influence of acid etching conditions on the microstructure of the Ti-13Nb-13Zr alloys as well as on the rate of HCA formation was evaluated using SEM-EDS, FTIR, and gravimetric analyses. Results: Sintered Ti-13Nb-13Zr alloys consist of a Widmannst{\"a}tten (α + β) microstructure. Exposure of chemically etched and NaOH activated samples to SBF for 1 week leads to the formation of a HCA layer on the surface of HCl as well as H3PO4 treated samples. No HCA formation was found on HNO3 treated samples. After 2 weeks in SBF the mass increase, that can be correlated to the HCA formation rate, was the highest for HCl pretreated samples (2.4 mg/cm2) followed by H3PO4 (0.8 mg/cm2) and HNO3 pretreated ones (0.2 mg/cm2). Significance: Since the in vitro HCA formation from SBF is generally accepted as a typical feature for bioactive materials, it is supposed that HCl etching with subsequent NaOH treatment might enhance the in vivo bone-bonding ability of Ti-13Nb-13Zr.",
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AU - Müller, Frank A.

AU - Bottino, Marco C.

AU - Müller, Lenka

AU - Henriques, Vinicius A R

AU - Lohbauer, Ulrich

AU - Bressiani, Ana Helena A

AU - Bressiani, José C.

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KW - Surface modification

KW - Titanium alloys

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