In vivo detection of cavitation induced by lithotripsy shock waves in pig kidney

O. Sapozhnikov, M. Bailey, L. Crum, R. Cleveland, S. Vaezy, J. McAteer, A. Evan

Research output: Contribution to journalConference article

Abstract

The procedure of extracorporeal shock wave lithotripsy (ESWL) has been in clinical use for over 15 years, however, the physical mechanisms of stone comminution and possible permanent damage to treated kidneys are still not well understood. It is now recognized that a clinical dose of shock waves required to fragment stones will induce renal injury in a majority, if not all, treated kidneys. One mechanism that appears to play a significant role in this tissue damage is acoustic cavitation. In our preliminary in vitro work we have developed a dual passive cavitation detector for use in lithotripsy which consists of a pair of confocal piezoceramic receivers and a coincidence detection algorithm. This system enables us to improve the spatial resolution of where cavitation events are detected. Experiments were performed with pigs (15-30 kg, 3-6 weeks) using Dornier HM3 lithotripter. Efforts at in vivo registration of cavitation detection sites are discussed.

Original languageEnglish (US)
Pages (from-to)A64
JournalUltrasound in Medicine and Biology
Volume26
Issue numberSUPPL. 2
StatePublished - Jan 1 2000
EventThe 9th Congress of World Federation for Ultrasound in Medicine and Biology - Florence, Italy
Duration: May 6 2000May 10 2000

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ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

Cite this

Sapozhnikov, O., Bailey, M., Crum, L., Cleveland, R., Vaezy, S., McAteer, J., & Evan, A. (2000). In vivo detection of cavitation induced by lithotripsy shock waves in pig kidney. Ultrasound in Medicine and Biology, 26(SUPPL. 2), A64.