In vivo effects of acute EtOH on rat α and β luteinizing hormone gene expression

M. A. Emanuele, J. Tentler, N. V. Emanuele, Mark Kelley

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The suppressive effects of ethanol (EtOH) on the male rodent reproductive axis, especially on serum luteinizing hormone (LH) levels, are well known. In this study we examined, in coordinate fashion, the effects of EtOH on LH secretion and on steady-state levels of the mRNA for the two genes that direct LH synthesis, namely α- and β-LH. A single intraperitoneal (IP) injection of EtOH given to castrated male rats produced a statistically significant fall in serum LH levels at 1.5 (p

Original languageEnglish (US)
Pages (from-to)345-348
Number of pages4
JournalAlcohol
Volume8
Issue number5
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Luteinizing Hormone
Gene expression
Rats
Gene Expression
Intraperitoneal Injections
Serum
Rodentia
Ethanol
Genes
Messenger RNA

Keywords

  • EtOH
  • LH
  • mRNA

ASJC Scopus subject areas

  • Biochemistry
  • Medicine(all)
  • Neuroscience(all)
  • Behavioral Neuroscience
  • Toxicology
  • Health(social science)

Cite this

In vivo effects of acute EtOH on rat α and β luteinizing hormone gene expression. / Emanuele, M. A.; Tentler, J.; Emanuele, N. V.; Kelley, Mark.

In: Alcohol, Vol. 8, No. 5, 1991, p. 345-348.

Research output: Contribution to journalArticle

Emanuele, M. A. ; Tentler, J. ; Emanuele, N. V. ; Kelley, Mark. / In vivo effects of acute EtOH on rat α and β luteinizing hormone gene expression. In: Alcohol. 1991 ; Vol. 8, No. 5. pp. 345-348.
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