Incidence of persistent left superior vena cava in esophageal atresia

Nathan Mowery, Deborah F. Billmire, Marcus Schamberger, Paul Szotek, Karen W. West, Frederick Rescorla, L. R. Scherer, Scott Engum, Thomas Rouse, Jay L. Grosfeld

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: Esophageal atresia is known to be associated with a variety of additional congenital anomalies in multiple organ systems. Emphasis on cardiovascular anomalies has been focused on aortic arch and intrinsic cardiac malformations. Persistent left superior vena cava (PLSVC) is the most common venous thoracic anomaly in the general population and creates a problem when central venous access is required. This review was undertaken to define the incidence of PLSVC in infants with esophageal atresia and to determine if any subgroup of associated anomalies poses additional risk. Methods: A retrospective, institutional review board-approved review of all children treated for esophageal atresia from 1993 to 2002 at Riley Hospital for Children was undertaken. Of 118 children, 89 had sufficient data for inclusion. Charts were reviewed for gestational age, weight, type of atresia, echocardiogram, and associated anomalies. Statistical analysis was performed using the Fisher's Exact test. Results: Of 89 children, 8 (9.9%; confidence interval, 4%-17%) had PLSVC compared with the reported incidence of 0.3% in the general population. Presence of additional organ system anomalies did not significantly increase relative risk for PLSVC. Conclusion: The incidence of PLSVC is significantly increased in children with esophageal atresia when compared with the general population. This increased incidence of PLSVC is not influenced by the presence of cardiac or other associated anomalies. This finding should be kept in mind when central venous access is required in this patient population.

Original languageEnglish
Pages (from-to)484-486
Number of pages3
JournalJournal of Pediatric Surgery
Volume41
Issue number3
DOIs
StatePublished - Mar 2006

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Esophageal Atresia
Superior Vena Cava
Incidence
Population
Research Ethics Committees
Thoracic Aorta
Gestational Age
Thorax
Confidence Intervals
Weights and Measures

Keywords

  • Esophageal atresia
  • Left superior vena cava
  • VATER association

ASJC Scopus subject areas

  • Surgery

Cite this

Mowery, N., Billmire, D. F., Schamberger, M., Szotek, P., West, K. W., Rescorla, F., ... Grosfeld, J. L. (2006). Incidence of persistent left superior vena cava in esophageal atresia. Journal of Pediatric Surgery, 41(3), 484-486. https://doi.org/10.1016/j.jpedsurg.2005.10.094

Incidence of persistent left superior vena cava in esophageal atresia. / Mowery, Nathan; Billmire, Deborah F.; Schamberger, Marcus; Szotek, Paul; West, Karen W.; Rescorla, Frederick; Scherer, L. R.; Engum, Scott; Rouse, Thomas; Grosfeld, Jay L.

In: Journal of Pediatric Surgery, Vol. 41, No. 3, 03.2006, p. 484-486.

Research output: Contribution to journalArticle

Mowery, N, Billmire, DF, Schamberger, M, Szotek, P, West, KW, Rescorla, F, Scherer, LR, Engum, S, Rouse, T & Grosfeld, JL 2006, 'Incidence of persistent left superior vena cava in esophageal atresia', Journal of Pediatric Surgery, vol. 41, no. 3, pp. 484-486. https://doi.org/10.1016/j.jpedsurg.2005.10.094
Mowery, Nathan ; Billmire, Deborah F. ; Schamberger, Marcus ; Szotek, Paul ; West, Karen W. ; Rescorla, Frederick ; Scherer, L. R. ; Engum, Scott ; Rouse, Thomas ; Grosfeld, Jay L. / Incidence of persistent left superior vena cava in esophageal atresia. In: Journal of Pediatric Surgery. 2006 ; Vol. 41, No. 3. pp. 484-486.
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