Increased and decreased preference for saccharin immediately following injections of various agents

Charles L. Kutscher, Bryan K. Yamamoto, Jeffry N. Hamburger

Research output: Contribution to journalArticle

5 Scopus citations


Rats pretrained for preference testing and injected with LiCl showed a reduction of saccharin preference in a test with a novel saccharin solution paired with water given 15 min following the injection. Previous exposure to the saccharin solution precluded this selective depression of drinking. In a second experiment, using rats naive to saccharin, insulin injection produced an increase, 2-DG and hypertonic NaCl produced a decrease, and saccharin injection produced no change in saccharin preference.

Original languageEnglish (US)
Pages (from-to)461-464
Number of pages4
JournalPhysiology and Behavior
Issue number3
StatePublished - Sep 1979



  • 2-Deoxyglucose
  • Insulin
  • LiCl
  • NaCl
  • Saccharin
  • Taste aversion
  • Taste preference

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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