Indiana University kidney transplant program: overview and summary of the last 1022 kidney alone transplants with at least 1 year follow-up.

William Goggins, John Powelson, Jonathan Fridell, Dennis Mishler, Muhammad Yaqub, Jeanne Chen, Asif Sharfuddin, Tim Taber, Martin Milgrom

Research output: Contribution to journalArticle

Abstract

Indiana University's kidney transplant program has undergone changes in the program's approach to immunosuppression. This change in philosophy has moved the program away from multiple chronic maintenance immunosuppression strategies with corticosteroids to steroid-free maintenance immunosuppressive strategies for both adults and pediatric recipients. Anti-thymocyte globulin induction (beginning pre-reperfusion) has allowed for the rapid post-transplant withdrawal of corticosteroids. Steroid-free maintenance immunosuppression has been achieved with excellent patient and graft survival as well as lower rejection rates in the first posttransplant year. Desensitized recipients can also be safely included in steroid-free protocols. The administration of anti-thymocyte globulin prereperfusion combined with pulsatile perfusion storage of deceased donor kidneys has led to an extremely low delayed graft function rate.

Original languageEnglish (US)
Pages (from-to)135-142
Number of pages8
JournalClinical transplants
StatePublished - 2009

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Immunosuppression
Antilymphocyte Serum
Steroids
Maintenance
Transplants
Kidney
Adrenal Cortex Hormones
Delayed Graft Function
Pulsatile Flow
Graft Survival
Immunosuppressive Agents
Reperfusion
Tissue Donors
Pediatrics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Indiana University kidney transplant program : overview and summary of the last 1022 kidney alone transplants with at least 1 year follow-up. / Goggins, William; Powelson, John; Fridell, Jonathan; Mishler, Dennis; Yaqub, Muhammad; Chen, Jeanne; Sharfuddin, Asif; Taber, Tim; Milgrom, Martin.

In: Clinical transplants, 2009, p. 135-142.

Research output: Contribution to journalArticle

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