Infant mortality and the risk of small size for gestational age in the subsequent pregnancy: A retrospective cohort study

Hamisu M. Salihu, Euna M. August, Cara De La Cruz, Mulubrhan F. Mogos, Hanna Weldeselasse, Amina P. Alio

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

To examine the association between prior infant mortality and subsequent risk for small for gestational age (SGA). This population-based, retrospective cohort study used the Missouri maternally linked, longitudinal dataset (1989-2005). Analyses were restricted to women who had two singleton pregnancies during the study period. Logistic regression was conducted to obtain adjusted odds ratios (AOR) and 95 % confidence intervals (CI) for the association between infant mortality in the first pregnancy and SGA in the second pregnancy. Women with a prior occurrence of infant death were more likely to be black and obese and had lower educational levels and had higher rates of pregnancy-related complications (p <0.01). White women with previous infant mortality were at 1.46 times greater risk for SGA in the subsequent pregnancy (AOR = 1.46, 95 % CI = 1.24-1.71). For black women with prior infant death, the risk for SGA increased to 2.77 times (AOR = 2.77, 95 % CI = 2.19-3.51). White mothers who experienced infant mortality coupled with SGA in the first pregnancy had a nearly threefold heightened risk for SGA in the second pregnancy (AOR = 2.89, 95 % CI = 2.21-3.78), whereas black women with this history were more than four times as likely to have an infant with SGA (AOR = 4.60 95 % CI = 3.05-6.96). Prior occurrence of infant mortality is associated with increased risk for subsequent SGA. This finding has important implications for health professionals, as targeted inter-conception strategies for women who have experienced infant death, as well as SGA, may be warranted.

Original languageEnglish (US)
Pages (from-to)1044-1051
Number of pages8
JournalMaternal and Child Health Journal
Volume17
Issue number6
DOIs
StatePublished - Aug 2013
Externally publishedYes

Fingerprint

Infant Mortality
Gestational Age
Cohort Studies
Retrospective Studies
Pregnancy
Odds Ratio
Confidence Intervals
Small for Gestational Age Infant
Pregnancy Complications
Logistic Models
History
Mothers
Health
Population
Infant Death

Keywords

  • Birth outcomes
  • Health disparities
  • Infant mortality
  • Pregnancy
  • Small for gestational age

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Epidemiology
  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)

Cite this

Infant mortality and the risk of small size for gestational age in the subsequent pregnancy : A retrospective cohort study. / Salihu, Hamisu M.; August, Euna M.; De La Cruz, Cara; Mogos, Mulubrhan F.; Weldeselasse, Hanna; Alio, Amina P.

In: Maternal and Child Health Journal, Vol. 17, No. 6, 08.2013, p. 1044-1051.

Research output: Contribution to journalArticle

Salihu, Hamisu M. ; August, Euna M. ; De La Cruz, Cara ; Mogos, Mulubrhan F. ; Weldeselasse, Hanna ; Alio, Amina P. / Infant mortality and the risk of small size for gestational age in the subsequent pregnancy : A retrospective cohort study. In: Maternal and Child Health Journal. 2013 ; Vol. 17, No. 6. pp. 1044-1051.
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