Influence of the organic matrix on root dentine erosion by citric acid

A. T. Hara, M. Ando, J. A. Cury, M. C. Serra, C. González-Cabezas, D. T. Zero

Research output: Contribution to journalArticle

68 Scopus citations


This investigation was conducted in an attempt to clarify the role of the organic matrix in bovine dentine demineralisation by 1% citric acid. Dentine slabs (n = 15) were treated for 2 min with 10% sodium hypochlorite (NaOCl, a strong protein solvent), 2% glutaraldehyde (GDA, a protein fixative) or deionised water (DIW, as negative control) prior to each of 5 demineralisation periods of 30 min. The mineral loss (ΔZ), lesion depth (LD) and surface loss (SL) were determined after each period of demineralisation, by transverse microradiography. The NaOCl-treated group showed higher ΔZ and LD than the GDA- and DIW-treated groups. No differences between GDA and DIW groups were found. The AZ and LD profiles were explained by quadratic fits (r2> 0.80; p = 0.001) in all groups. SL was detected only in the NaOCl-treated group. The data suggested that the maintenance of the organic matrix in the lesion might be important to reduce the erosion progression rate.

Original languageEnglish (US)
Pages (from-to)134-138
Number of pages5
JournalCaries research
Issue number2
StatePublished - Mar 1 2005


  • Demineralisation
  • Erosion
  • Organic matrix
  • Root dentine

ASJC Scopus subject areas

  • Dentistry(all)

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