Initial evaluation of the Indiana small animal PET scanner

Ned C. Rouze, Victor C. Soon, John W. Young, Stefan Siegel, Gary Hutchins

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

The Indiana small animal PET scanner is a new generation PET scanner with design goals of 1 microliter volumetric spatial resolution, a point source sensitivity of greater than 5 percent, and an imaging field-of-view suitable for whole body mouse imaging. The scanner design uses 12 planar detector banks each consisting of a 48 × 108 array of 20 mm long LSO crystals with an array pitch of 0.87 mm coupled to two Hamamatsu H8500 large area, 64-anode photomultiplier tubes. The detector modules are mounted on a rotatable gantry and are offset from the center of rotation to give an increased sampling density. Eight detector banks are currently installed in the scanner, and this report presents an initial performance evaluation of the scanner for this configuration. Using a 30 gauge needle (ID=0.15 mm, OD=0.30 mm) positioned near the center of the scanner, the transaxial resolution has been measured to be 1.1 mm FWHM and the axial resolution has been measured to be 1.5 mm FWHM. The sensitivity has been measured to be 4.0% of all decays. The scatter fraction is 0.26 and the peak noise equivalent countrate is 80 kcps at an activity of 0.22 mCi. Sample images demonstrate good imaging capabilities.

Original languageEnglish
Title of host publicationIEEE Nuclear Science Symposium Conference Record
Pages2394-2398
Number of pages5
Volume4
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Other

OtherNuclear Science Symposium Conference Record, 2005 IEEE
CountryPuerto Rico
Period10/23/0510/29/05

Fingerprint

Animals
Full width at half maximum
Detectors
Imaging techniques
Electron tubes
Photomultipliers
Needles
Gages
Anodes
Sampling
Crystals

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Rouze, N. C., Soon, V. C., Young, J. W., Siegel, S., & Hutchins, G. (2005). Initial evaluation of the Indiana small animal PET scanner. In IEEE Nuclear Science Symposium Conference Record (Vol. 4, pp. 2394-2398). [1596815] https://doi.org/10.1109/NSSMIC.2005.1596815

Initial evaluation of the Indiana small animal PET scanner. / Rouze, Ned C.; Soon, Victor C.; Young, John W.; Siegel, Stefan; Hutchins, Gary.

IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. p. 2394-2398 1596815.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rouze, NC, Soon, VC, Young, JW, Siegel, S & Hutchins, G 2005, Initial evaluation of the Indiana small animal PET scanner. in IEEE Nuclear Science Symposium Conference Record. vol. 4, 1596815, pp. 2394-2398, Nuclear Science Symposium Conference Record, 2005 IEEE, Puerto Rico, 10/23/05. https://doi.org/10.1109/NSSMIC.2005.1596815
Rouze NC, Soon VC, Young JW, Siegel S, Hutchins G. Initial evaluation of the Indiana small animal PET scanner. In IEEE Nuclear Science Symposium Conference Record. Vol. 4. 2005. p. 2394-2398. 1596815 https://doi.org/10.1109/NSSMIC.2005.1596815
Rouze, Ned C. ; Soon, Victor C. ; Young, John W. ; Siegel, Stefan ; Hutchins, Gary. / Initial evaluation of the Indiana small animal PET scanner. IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. pp. 2394-2398
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