Intensive Care Management of Pediatric Acute Liver Failure

Riad Lutfi, Kamal Abulebda, Mara E. Nitu, Jean P. Molleston, Molly A. Bozic, Girish Subbarao

Research output: Contribution to journalReview article

11 Scopus citations


Pediatric acute liver failure is rare but life-threatening illness that occurs in children without preexisting liver disease. The rarity of the disease, along with its severity and heterogeneity, presents unique clinical challenges to the physicians providing care for pediatric patients with acute liver failure. In this review, practical clinical approaches to the care of critically ill children with acute liver failure are discussed with an organ system-specific approach. The underlying pathophysiological processes, major areas of uncertainty, and approaches to the critical care management of pediatric acute liver failure are also reviewed.

Original languageEnglish (US)
Pages (from-to)660-670
Number of pages11
JournalJournal of pediatric gastroenterology and nutrition
Issue number5
StatePublished - May 1 2017


  • acute liver failure
  • critical care
  • hepatic encephalopathy
  • liver transplantation
  • multiple organ systems
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

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