Interaction between human neutrophils and group B streptococci (GBS) and group antigens, monitored by Luminol-dependent chemiluminescence

Michael Kowolik, C. G. Cumming, M. Grant

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Interaction between the 5 serotypes of GBS and human neutrophils was investigated using Luminol-dependent chemiluminescence. A considerable variation in response, and a variable dependence on pre-opsonisation was demonstrated both for whole bacteria and HCl-extracts. These preliminary results may have relevance to clinical infection with GBS and demonstrate hitherto unrecognised differences in the nature of 'group-specific' antigen extracts from GBS serotypes.

Original languageEnglish (US)
Pages (from-to)55-58
Number of pages4
JournalJournal of Clinical and Laboratory Immunology
Volume8
Issue number1
StatePublished - 1982
Externally publishedYes

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Luminol
Streptococcus agalactiae
Luminescence
Neutrophils
Antigens
Bacteria
Infection
Serogroup

ASJC Scopus subject areas

  • Immunology

Cite this

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abstract = "Interaction between the 5 serotypes of GBS and human neutrophils was investigated using Luminol-dependent chemiluminescence. A considerable variation in response, and a variable dependence on pre-opsonisation was demonstrated both for whole bacteria and HCl-extracts. These preliminary results may have relevance to clinical infection with GBS and demonstrate hitherto unrecognised differences in the nature of 'group-specific' antigen extracts from GBS serotypes.",
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AU - Cumming, C. G.

AU - Grant, M.

PY - 1982

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AB - Interaction between the 5 serotypes of GBS and human neutrophils was investigated using Luminol-dependent chemiluminescence. A considerable variation in response, and a variable dependence on pre-opsonisation was demonstrated both for whole bacteria and HCl-extracts. These preliminary results may have relevance to clinical infection with GBS and demonstrate hitherto unrecognised differences in the nature of 'group-specific' antigen extracts from GBS serotypes.

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