Interleukin-13 Is Unlucky for Allergy Sufferers

Markus M. Xie, Alexander L. Dent

Research output: Contribution to journalShort surveypeer-review


Anaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-specific IgE. Gowthaman et al. now show that a new interleukin (IL)-13-expressing T helper cell subset specifically promotes high-affinity IgE responses. The discovery of T follicular helper (Tfh)13 cells defines potential new targets for allergy therapies.

Original languageEnglish (US)
Pages (from-to)714-716
Number of pages3
JournalTrends in Pharmacological Sciences
Issue number10
StatePublished - Oct 2019


  • Tfh13
  • allergy
  • anaphylaxis

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

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