Interleukin-13 Is Unlucky for Allergy Sufferers

Markus M. Xie, Alexander Dent

Research output: Contribution to journalShort survey

Abstract

Anaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-specific IgE. Gowthaman et al. now show that a new interleukin (IL)-13-expressing T helper cell subset specifically promotes high-affinity IgE responses. The discovery of T follicular helper (Tfh)13 cells defines potential new targets for allergy therapies.

Original languageEnglish (US)
JournalTrends in Pharmacological Sciences
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Allergies
Interleukin-13
Immunoglobulin E
Hypersensitivity
T-Lymphocyte Subsets
Anaphylaxis
Helper-Inducer T-Lymphocytes
Allergens
Therapeutics

Keywords

  • allergy
  • anaphylaxis
  • Tfh13

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

Cite this

Interleukin-13 Is Unlucky for Allergy Sufferers. / Xie, Markus M.; Dent, Alexander.

In: Trends in Pharmacological Sciences, 01.01.2019.

Research output: Contribution to journalShort survey

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