Interuncal distance as a measure of hippocampal atrophy: Normative data on axial MR imaging

P. M. Doraiswamy, W. M. McDonald, L. Patterson, M. M. Husain, G. S. Figiel, O. B. Boyko, K. R. Krishnan

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Abstract

PURPOSE: To assess the effects of age and gender on the interuncal distance measured from MR images. METHODS: High-field strength MR Images (axial) of 75 volunteers, 21-82 years old and free of neurologic disorders, were used to measure the interuncal distance. RESULTS: The interuncal distance increased with age (r = 0.66, P <.0001). The mean (SD) interuncal distance for all subjects was 21.4 (4) mm with a range of 12 to 29 mm. CONCLUSIONS: The interuncal distance in healthy subjects is unlikely to exceed 30 mm. Our data may be of clinical significance in view of a previous report stating that the interuncal distance may be enlarged in pathologic hippocampal degeneration, such as in patients with Alzheimer disease.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume14
Issue number1
StatePublished - Jan 1 1993

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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Doraiswamy, P. M., McDonald, W. M., Patterson, L., Husain, M. M., Figiel, G. S., Boyko, O. B., & Krishnan, K. R. (1993). Interuncal distance as a measure of hippocampal atrophy: Normative data on axial MR imaging. American Journal of Neuroradiology, 14(1), 141-143.