Intervention in necrotizing pancreatitis: An evidence-based review of surgical and percutaneous alternatives

Edward L. Bradley, Thomas J. Howard, Eric Van Sonnenberg, Mehran Fotoohi

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Interventional therapy in necrotizing pancreatitis is evolving. Efforts to modify or prevent pancreatic necrosis by intra-arterial infusion of antibiotics and antiproteases have been described. Moreover, traditional approaches to the surgical management of infected pancreatic necrosis are being challenged by a host of endoscopic and percutaneous techniques. While these approaches are potentially valuable additions to interventional therapy in necrotizing pancreatitis, few evidence-based studies are available to support their supplanting more traditional approaches at this time. Cooperative evidence-based multiinstitutional studies will be required to address the validity of these proposals.

Original languageEnglish (US)
Pages (from-to)634-639
Number of pages6
JournalJournal of Gastrointestinal Surgery
Volume12
Issue number4
DOIs
StatePublished - Apr 1 2008

Keywords

  • Continuous regional intraarterial protease infusion
  • Guided percutaneous drainage
  • Infected necrosis
  • Laparoscopy
  • Minimally invasive
  • Pancreatic necrosis
  • Surgical debridement

ASJC Scopus subject areas

  • Surgery

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