Intracast muscle stimulation prevents bone and cartilage deterioration in cast-immobilized rabbits

David Burr, R. G. Frederickson, C. Pavlinch, M. Sickles, S. Burkart

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Tibial articular cartilage and the knee meniscus from cast-immobilized rabbits whose quadriceps were electrically stimulated for 17 days were compared with those from cast-immobilized rabbits without muscle stimulation. Cartilage from non-stimulated rabbits showed evidence of deep fibrillation and loss of Safranin O metachromasia. Scanning electron microscopy (SEM) showed large areas of cavitation and cartilage erosion. Cartilage from cast-immobilized muscle-stimulated rabbits demonstrated no fibrillation, pitting, or surface erosion at either the light microscopic or SEM levels. Electrical muscle stimulation prevented bone loss by significantly increasing bone turnover rate. These observations suggest that electrical muscle stimulation can prevent bone and cartilage deterioration in short-term cast-immobilized limbs.

Original languageEnglish (US)
Pages (from-to)264-278
Number of pages15
JournalClinical Orthopaedics and Related Research
VolumeNO. 189
StatePublished - 1984
Externally publishedYes

Fingerprint

Cartilage
Rabbits
Bone and Bones
Muscles
Electron Scanning Microscopy
Electric Stimulation
Bone Remodeling
Articular Cartilage
Knee
Extremities
Light

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Burr, D., Frederickson, R. G., Pavlinch, C., Sickles, M., & Burkart, S. (1984). Intracast muscle stimulation prevents bone and cartilage deterioration in cast-immobilized rabbits. Clinical Orthopaedics and Related Research, NO. 189, 264-278.

Intracast muscle stimulation prevents bone and cartilage deterioration in cast-immobilized rabbits. / Burr, David; Frederickson, R. G.; Pavlinch, C.; Sickles, M.; Burkart, S.

In: Clinical Orthopaedics and Related Research, Vol. NO. 189, 1984, p. 264-278.

Research output: Contribution to journalArticle

Burr, D, Frederickson, RG, Pavlinch, C, Sickles, M & Burkart, S 1984, 'Intracast muscle stimulation prevents bone and cartilage deterioration in cast-immobilized rabbits', Clinical Orthopaedics and Related Research, vol. NO. 189, pp. 264-278.
Burr, David ; Frederickson, R. G. ; Pavlinch, C. ; Sickles, M. ; Burkart, S. / Intracast muscle stimulation prevents bone and cartilage deterioration in cast-immobilized rabbits. In: Clinical Orthopaedics and Related Research. 1984 ; Vol. NO. 189. pp. 264-278.
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