Intraductal papillary mucinous neoplasm of the pancreas, one manifestation of a more systemic disease?

Alexandra M. Roch, Carlo Maria Rosati, Jessica L. Cioffi, Eugene P. Ceppa, John DeWitt, Mohammad A. Al-Haddad, Michael House, Nicholas Zyromski, Attila Nakeeb, C. Schmidt

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background Several studies have demonstrated a high prevalence of extrapancreatic malignancies, and an association with autoimmune pancreatitis in patients with intraductal papillary mucinous neoplasm (IPMN). We hypothesized that IPMNs were associated with an increase rate of systemic diseases. Methods From 1996 to 2013, a retrospective analysis of a prospectively collected database was performed and supplemented with electronic medical charts review. Results Two hundred twenty extrapancreatic malignancies were found in 185 patients (22%) compared with expected 5% in the general population. Colorectal, lung, and renal cell carcinoma had significant observed/expected ratios (P

Original languageEnglish (US)
Pages (from-to)512-518
Number of pages7
JournalAmerican Journal of Surgery
Volume211
Issue number3
DOIs
StatePublished - Mar 1 2016

Fingerprint

Pancreatic Neoplasms
Medical Electronics
Neoplasms
Renal Cell Carcinoma
Pancreatitis
Databases
Lung
Population

Keywords

  • Autoimmune diseases
  • Extrapancreatic malignancies
  • Incidence
  • Intraductal papillary mucinous neoplasm

ASJC Scopus subject areas

  • Surgery

Cite this

Intraductal papillary mucinous neoplasm of the pancreas, one manifestation of a more systemic disease? / Roch, Alexandra M.; Rosati, Carlo Maria; Cioffi, Jessica L.; Ceppa, Eugene P.; DeWitt, John; Al-Haddad, Mohammad A.; House, Michael; Zyromski, Nicholas; Nakeeb, Attila; Schmidt, C.

In: American Journal of Surgery, Vol. 211, No. 3, 01.03.2016, p. 512-518.

Research output: Contribution to journalArticle

Roch, Alexandra M. ; Rosati, Carlo Maria ; Cioffi, Jessica L. ; Ceppa, Eugene P. ; DeWitt, John ; Al-Haddad, Mohammad A. ; House, Michael ; Zyromski, Nicholas ; Nakeeb, Attila ; Schmidt, C. / Intraductal papillary mucinous neoplasm of the pancreas, one manifestation of a more systemic disease?. In: American Journal of Surgery. 2016 ; Vol. 211, No. 3. pp. 512-518.
@article{98879cf3c7944d8ab18811f0459222b7,
title = "Intraductal papillary mucinous neoplasm of the pancreas, one manifestation of a more systemic disease?",
abstract = "Background Several studies have demonstrated a high prevalence of extrapancreatic malignancies, and an association with autoimmune pancreatitis in patients with intraductal papillary mucinous neoplasm (IPMN). We hypothesized that IPMNs were associated with an increase rate of systemic diseases. Methods From 1996 to 2013, a retrospective analysis of a prospectively collected database was performed and supplemented with electronic medical charts review. Results Two hundred twenty extrapancreatic malignancies were found in 185 patients (22{\%}) compared with expected 5{\%} in the general population. Colorectal, lung, and renal cell carcinoma had significant observed/expected ratios (P",
keywords = "Autoimmune diseases, Extrapancreatic malignancies, Incidence, Intraductal papillary mucinous neoplasm",
author = "Roch, {Alexandra M.} and Rosati, {Carlo Maria} and Cioffi, {Jessica L.} and Ceppa, {Eugene P.} and John DeWitt and Al-Haddad, {Mohammad A.} and Michael House and Nicholas Zyromski and Attila Nakeeb and C. Schmidt",
year = "2016",
month = "3",
day = "1",
doi = "10.1016/j.amjsurg.2015.12.009",
language = "English (US)",
volume = "211",
pages = "512--518",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Intraductal papillary mucinous neoplasm of the pancreas, one manifestation of a more systemic disease?

AU - Roch, Alexandra M.

AU - Rosati, Carlo Maria

AU - Cioffi, Jessica L.

AU - Ceppa, Eugene P.

AU - DeWitt, John

AU - Al-Haddad, Mohammad A.

AU - House, Michael

AU - Zyromski, Nicholas

AU - Nakeeb, Attila

AU - Schmidt, C.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Background Several studies have demonstrated a high prevalence of extrapancreatic malignancies, and an association with autoimmune pancreatitis in patients with intraductal papillary mucinous neoplasm (IPMN). We hypothesized that IPMNs were associated with an increase rate of systemic diseases. Methods From 1996 to 2013, a retrospective analysis of a prospectively collected database was performed and supplemented with electronic medical charts review. Results Two hundred twenty extrapancreatic malignancies were found in 185 patients (22%) compared with expected 5% in the general population. Colorectal, lung, and renal cell carcinoma had significant observed/expected ratios (P

AB - Background Several studies have demonstrated a high prevalence of extrapancreatic malignancies, and an association with autoimmune pancreatitis in patients with intraductal papillary mucinous neoplasm (IPMN). We hypothesized that IPMNs were associated with an increase rate of systemic diseases. Methods From 1996 to 2013, a retrospective analysis of a prospectively collected database was performed and supplemented with electronic medical charts review. Results Two hundred twenty extrapancreatic malignancies were found in 185 patients (22%) compared with expected 5% in the general population. Colorectal, lung, and renal cell carcinoma had significant observed/expected ratios (P

KW - Autoimmune diseases

KW - Extrapancreatic malignancies

KW - Incidence

KW - Intraductal papillary mucinous neoplasm

UR - http://www.scopus.com/inward/record.url?scp=84959487220&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959487220&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2015.12.009

DO - 10.1016/j.amjsurg.2015.12.009

M3 - Article

C2 - 26830712

AN - SCOPUS:84959487220

VL - 211

SP - 512

EP - 518

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 3

ER -