Intramedullary spinal cord metastasis (ISCM) in renal cell carcinoma: A series of six cases

M. Fakih, D. Schiff, R. Erlich, T. F. Logan

Research output: Contribution to journalArticle

52 Scopus citations


Intramedullary spinal cord metastasis (ISCM) has been infrequently diagnosed during the clinical course of renal cell carcinoma (RCC). With the advent of more sensitive diagnostic procedures including magnetic resonance imaging (MRI), more cases of ISCM have been documented. The management of these cases is particularly challenging as lack of prompt intervention often results in irreversible progressive neurological deficits. We describe the management and clinical course in six patients with RCC who developed ISCM. Two of these patients were treated surgically while four were treated with radiation therapy (RT). Although no major improvements in neurological function were noted, stabilizations were common. This prolonged their ability to live independently, a matter of utmost importance in these terminally ill patients.

Original languageEnglish (US)
Pages (from-to)1173-1177
Number of pages5
JournalAnnals of Oncology
Issue number8
StatePublished - Aug 2001


  • Intramedullary metastasis
  • Radiation therapy
  • Renal cell carcinoma
  • Spinal cord tumors

ASJC Scopus subject areas

  • Hematology
  • Oncology

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