Abstract
We sought to determine the patient and plaque characteristics associated with the different forms of arterial remodeling as seen by intravascular ultrasound (IVUS) before coronary intervention. Remodeling in response to plaque accumulation may occur in the form of compensatory enlargement and/or focal vessel contraction. Previous studies report variation in the frequency and form of arterial remodeling. We performed preintervention IVUS imaging on 169 patients. Vessels were categorized as exhibiting compensatory enlargement or focal contraction if the arterial area at the lesion was larger or smaller, respectively, than both proximal and distal reference arterial areas; otherwise the artery was considered not to have undergone significant remodeling. Calcification was assessed and noncalcified plaque density was measured by videodensitometry. Sixty-one of 169 patients (66 narrowings) (46 men and 15 women, age 56 ± 11 years) had adequate reference segments. Remodeling occurred in 43 of 66 patients (65%): compensatory enlargement in 27 of 66 (41%) and focal contraction in 16 of 66 (24%). Lesions with focal contraction had significantly smaller arterial area (13.3 ± 3.3 vs 18.1 ± 7.0 mm2, p = 0.02) and plaque area (9.5 ± 2.8 vs 13.7 ± 5.5 mm2, p
| Original language | English (US) |
|---|---|
| Pages (from-to) | 37-40 |
| Number of pages | 4 |
| Journal | The American Journal of Cardiology |
| Volume | 84 |
| Issue number | 1 |
| State | Published - Jul 1 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling. / Weissman, Neil J.; Sheris, Steven J.; Chari, Ravi; Mendelsohn, Farrell O.; Anderson, William D.; Breall, Jeffrey; Tanguay, Jean Francois; Diver, Daniel J.
In: The American Journal of Cardiology, Vol. 84, No. 1, 01.07.1999, p. 37-40.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling
AU - Weissman, Neil J.
AU - Sheris, Steven J.
AU - Chari, Ravi
AU - Mendelsohn, Farrell O.
AU - Anderson, William D.
AU - Breall, Jeffrey
AU - Tanguay, Jean Francois
AU - Diver, Daniel J.
PY - 1999/7/1
Y1 - 1999/7/1
N2 - We sought to determine the patient and plaque characteristics associated with the different forms of arterial remodeling as seen by intravascular ultrasound (IVUS) before coronary intervention. Remodeling in response to plaque accumulation may occur in the form of compensatory enlargement and/or focal vessel contraction. Previous studies report variation in the frequency and form of arterial remodeling. We performed preintervention IVUS imaging on 169 patients. Vessels were categorized as exhibiting compensatory enlargement or focal contraction if the arterial area at the lesion was larger or smaller, respectively, than both proximal and distal reference arterial areas; otherwise the artery was considered not to have undergone significant remodeling. Calcification was assessed and noncalcified plaque density was measured by videodensitometry. Sixty-one of 169 patients (66 narrowings) (46 men and 15 women, age 56 ± 11 years) had adequate reference segments. Remodeling occurred in 43 of 66 patients (65%): compensatory enlargement in 27 of 66 (41%) and focal contraction in 16 of 66 (24%). Lesions with focal contraction had significantly smaller arterial area (13.3 ± 3.3 vs 18.1 ± 7.0 mm2, p = 0.02) and plaque area (9.5 ± 2.8 vs 13.7 ± 5.5 mm2, p
AB - We sought to determine the patient and plaque characteristics associated with the different forms of arterial remodeling as seen by intravascular ultrasound (IVUS) before coronary intervention. Remodeling in response to plaque accumulation may occur in the form of compensatory enlargement and/or focal vessel contraction. Previous studies report variation in the frequency and form of arterial remodeling. We performed preintervention IVUS imaging on 169 patients. Vessels were categorized as exhibiting compensatory enlargement or focal contraction if the arterial area at the lesion was larger or smaller, respectively, than both proximal and distal reference arterial areas; otherwise the artery was considered not to have undergone significant remodeling. Calcification was assessed and noncalcified plaque density was measured by videodensitometry. Sixty-one of 169 patients (66 narrowings) (46 men and 15 women, age 56 ± 11 years) had adequate reference segments. Remodeling occurred in 43 of 66 patients (65%): compensatory enlargement in 27 of 66 (41%) and focal contraction in 16 of 66 (24%). Lesions with focal contraction had significantly smaller arterial area (13.3 ± 3.3 vs 18.1 ± 7.0 mm2, p = 0.02) and plaque area (9.5 ± 2.8 vs 13.7 ± 5.5 mm2, p
UR - http://www.scopus.com/inward/record.url?scp=0032984428&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032984428&partnerID=8YFLogxK
M3 - Article
C2 - 10404848
AN - SCOPUS:0032984428
VL - 84
SP - 37
EP - 40
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 1
ER -