Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling

Neil J. Weissman, Steven J. Sheris, Ravi Chari, Farrell O. Mendelsohn, William D. Anderson, Jeffrey Breall, Jean Francois Tanguay, Daniel J. Diver

Research output: Contribution to journalArticle

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Abstract

We sought to determine the patient and plaque characteristics associated with the different forms of arterial remodeling as seen by intravascular ultrasound (IVUS) before coronary intervention. Remodeling in response to plaque accumulation may occur in the form of compensatory enlargement and/or focal vessel contraction. Previous studies report variation in the frequency and form of arterial remodeling. We performed preintervention IVUS imaging on 169 patients. Vessels were categorized as exhibiting compensatory enlargement or focal contraction if the arterial area at the lesion was larger or smaller, respectively, than both proximal and distal reference arterial areas; otherwise the artery was considered not to have undergone significant remodeling. Calcification was assessed and noncalcified plaque density was measured by videodensitometry. Sixty-one of 169 patients (66 narrowings) (46 men and 15 women, age 56 ± 11 years) had adequate reference segments. Remodeling occurred in 43 of 66 patients (65%): compensatory enlargement in 27 of 66 (41%) and focal contraction in 16 of 66 (24%). Lesions with focal contraction had significantly smaller arterial area (13.3 ± 3.3 vs 18.1 ± 7.0 mm2, p = 0.02) and plaque area (9.5 ± 2.8 vs 13.7 ± 5.5 mm2, p

Original languageEnglish (US)
Pages (from-to)37-40
Number of pages4
JournalThe American Journal of Cardiology
Volume84
Issue number1
StatePublished - Jul 1 1999
Externally publishedYes

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Ultrasonics
Coronary Vessels
Ultrasonography
Arteries

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Weissman, N. J., Sheris, S. J., Chari, R., Mendelsohn, F. O., Anderson, W. D., Breall, J., ... Diver, D. J. (1999). Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling. The American Journal of Cardiology, 84(1), 37-40.

Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling. / Weissman, Neil J.; Sheris, Steven J.; Chari, Ravi; Mendelsohn, Farrell O.; Anderson, William D.; Breall, Jeffrey; Tanguay, Jean Francois; Diver, Daniel J.

In: The American Journal of Cardiology, Vol. 84, No. 1, 01.07.1999, p. 37-40.

Research output: Contribution to journalArticle

Weissman, NJ, Sheris, SJ, Chari, R, Mendelsohn, FO, Anderson, WD, Breall, J, Tanguay, JF & Diver, DJ 1999, 'Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling', The American Journal of Cardiology, vol. 84, no. 1, pp. 37-40.
Weissman, Neil J. ; Sheris, Steven J. ; Chari, Ravi ; Mendelsohn, Farrell O. ; Anderson, William D. ; Breall, Jeffrey ; Tanguay, Jean Francois ; Diver, Daniel J. / Intravascular ultrasonic analysis of plaque characteristics associated with coronary artery remodeling. In: The American Journal of Cardiology. 1999 ; Vol. 84, No. 1. pp. 37-40.
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