Intravitreal triamcinolone for choroidal neovascularization in ocular histoplasmosis syndrome

Ehud Rechtman, Valerie D. Allen, Ronald P. Danis, Linda M. Pratt, Alon Harris, Matthew A. Speicher

Research output: Contribution to journalArticle

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Abstract

PURPOSE: To report the effects of intravitreal triamcinolone acetonide injections for subfoveal and juxtafoveal choroidal neovascularization (CNV) in ocular histoplasmosis syndrome. METHODS: In a retrospective analysis, the proportion of eyes that gained ≥5 or lost ≥5 and ≥15 Early Treatment of Diabetic Retinopathy Study (ETDRS) letters, best-corrected visual acuity using ETDRS letter score (VA), greatest linear dimension (GLD), and treatment side effects were assessed. RESULTS: Ten patients (five subfoveal, five juxtafoveal CNV; median follow-up: 17 months; range, 6-41 months) were evaluated. Thirty percent gained ≥5 letters, 20% lost 5 to 14 letters, and 50% maintained stable VA. Overall, mean VA and GLD remained stable. Side effects were transient intraocular pressure elevation and mild cataract development. CONCLUSIONS: Intravitreal triamcinolone acetonide for CNV resulting from OHS was found to be relatively safe and showed good visual outcome for both subfoveal and juxtafoveal CNV. Further studies are warranted to evaluate this treatment.

Original languageEnglish (US)
Pages (from-to)739-741
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume136
Issue number4
DOIs
StatePublished - Oct 1 2003

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ASJC Scopus subject areas

  • Ophthalmology

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